Are you or someone you care about facing the symptoms of malaria, like high fever, chills, or body aches? If yes, chances are you’ve heard of Malarest Tablet, one of the most commonly prescribed medicines for malaria treatment.
Malaria is still a serious health threat in many parts of the world, especially in tropical regions. When it strikes, fast and effective treatment becomes a top priority, and that’s where Malarest Tablet comes in.
Known for its powerful combination of ingredients, Malarest Tablet is commonly prescribed by doctors to treat malaria quickly and safely. But with so many similar-sounding products out there, and questions about dosage, side effects, and cost, it’s easy to get confused.
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Malarest Tablet Uses – Malarest Dosage (Price, Benefits)

Table Of Contents
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What is Malarest?
Malarest Tablet
Malarest is a prescription anti-malarial medicine used to treat uncomplicated malaria caused by Plasmodium falciparum. It contains a powerful combination of Artemether and Lumefantrine, which work together to quickly kill malaria parasites and prevent the infection from coming back.

Malarest is a prescription anti-malarial medicine that’s specially designed to fight off malaria infections caused by Plasmodium falciparum the most dangerous type of malaria parasite. It is widely trusted by doctors because of its fast-acting and long-lasting effect.
Classification: Anti-Malarial Medicine
Malarest Tablet falls under the anti-malarial drug class and is used for acute, uncomplicated malaria. It doesn’t just treat the symptoms — it goes after the parasite causing the illness.
Combination of Two Powerful Ingredients
Malarest is a fixed-dose combination medicine that contains:
Ingredient | Role in Treatment |
---|---|
Artemether | Acts quickly to kill malaria parasites in the blood |
Lumefantrine | Prevents the parasites from coming back and ensures complete treatment |
Manufacturer & Country of Origin
- Brand Name: Malarest
- Manufactured By: Ipca Laboratories Ltd.
- Country of Origin: India
Available Forms of Malarest
Form | Description | Ideal For |
---|---|---|
Tablet | Solid form taken with water | Adults & older children |
Syrup | Liquid form that’s easy to swallow | Younger children & toddlers |
Is Malarest Over-the-Counter?
No. Malarest is a prescription-only medicine. That means you need a doctor’s recommendation before using it. Malaria treatment depends on proper diagnosis, so it’s important not to self-medicate.
Malarest Tablet Uses
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1. Primary Use: Treatment of Malaria (P. falciparum)
- Malarest Tablet is mainly used to treat uncomplicated malaria caused by Plasmodium falciparum, the most dangerous malaria parasite.
- It’s commonly recommended when the infection is not severe enough to require hospitalization.
- The combination of Artemether and Lumefantrine works together to kill the parasites and prevent their return.
2. Off-Label or Unapproved Uses (Very Limited)
- Malarest Tablet is not typically used for any other medical conditions apart from malaria.
- It is not advised for preventive use (prophylaxis) or for treating liver-stage malaria.
- Always consult a doctor before using it for anything outside its approved purpose.
3. Tablet vs Syrup – Is There a Difference in Use?
Form | Who It’s For | How It’s Used |
---|---|---|
Tablet | Adults & children (usually 12+) | Swallowed with water, usually after meals |
Syrup | Younger children or those who can’t swallow tablets | Measured dose taken with a spoon/dropper |
4. Is Malarest a Sleeping Pill?
- No, Malarest Tablet is NOT a sleeping pill.
- Many people confuse it with “Mela Rest”, which sounds similar but is not the same.
- Malarest Tablet treats malaria, not insomnia or anxiety. Always double-check the name when purchasing!
5. What Is the Use of the “3-Night Tablet”?
- Sometimes, Malarest Tablet is referred to as a “3-night tablet” because the full treatment usually lasts 3 days (6 doses).
- The tablets are taken over three nights in a specific schedule (e.g., at 0, 8, 24, 36, 48, and 60 hours).
- This helps completely eliminate the malaria parasite from the body and avoid relapse.
Malarest Syrup Uses For Children

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1. Main Use: Treating Malaria in Children
- Malarest Syrup is specially designed to treat uncomplicated malaria (Plasmodium falciparum) in younger children.
- It contains the same active ingredients as the tablet (Artemether + Lumefantrine), but in a liquid form that’s easier for kids to swallow.
2. Recommended Age for Use
- Usually prescribed for children aged 6 months and above, depending on body weight and severity.
- Always follow a doctor’s guidance when it comes to age and dosing.
3. Malarest Syrup Dose for Child
- The dosage is weight-based, not age-based.
- Your doctor will calculate the exact amount per kilogram of body weight.
- It is usually given twice a day for 3 days (total 6 doses).
- Never guess the dose — use the provided measuring cup or dropper and follow the doctor’s instructions.
4. Common Use Queries Answered
- “What are Malarest Syrup uses?” → It is used to treat malaria in children who can’t take tablets.
- “Is syrup safer than tablets?” → Both are equally safe and effective when used correctly. Syrup is just easier to give to small children who have difficulty swallowing tablets.
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How Does Malarest Work?
Malarest Tablet doesn’t just relieve malaria symptoms — it targets the root cause by killing the malaria parasites in the blood.
Mechanism of Action: Two Ingredients, One Powerful Combo
Malarest Tablet combines Artemether and Lumefantrine, both of which work in different but complementary ways:
Artemether – The Fast Attacker
- Artemether is a fast-acting anti-malarial.
- It quickly enters the bloodstream and kills the parasites by producing free radicals that damage their internal structure.
- It’s especially effective during the early stages of the parasite’s life cycle.
- Result: You or your child may start feeling better within 1–2 days of starting treatment.
Lumefantrine – The Long-Term Defender
- Lumefantrine has a slower onset but a longer duration of action.
- It targets the remaining parasites and prevents them from multiplying again.
- This reduces the chance of relapse or incomplete treatment, especially important in areas where drug resistance is common.
Lumefantrine – The Long-Term Defender
The combination ensures:
- Rapid symptom relief (thanks to Artemether)
- Sustained cure and lower relapse risk (thanks to Lumefantrine)
Comparison with Other Anti-Malarials
Medicine Name | Key Ingredients | How It Works | Notable Differences |
---|---|---|---|
Malarest | Artemether + Lumefantrine | Fast kill + Long protection | Commonly used in areas with high resistance |
Malarone | Atovaquone + Proguanil | Slows parasite growth and reproduction | Often used for prevention and travel medicine |
Sulfadoxine-Pyrimethamine (SP) | Sulfadoxine + Pyrimethamine | Blocks parasite DNA replication | Older drug, sometimes used in combination therapy |
Why Choose Malarest?
- Proven effective in regions with chloroquine-resistant malaria
- Easier to administer in children (syrup form available)
- Less risk of treatment failure or recurrence when the full 3-day course is followed
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Malarest Dosage
Category | Dosage Instructions | Duration | Notes |
---|---|---|---|
Adults | – Take 4 tablets initially (at 0 hours) – Then 4 tablets after 8 hours – Followed by 4 tablets every 12 hours for the next 2 days | Total 6 doses over 3 days | Take tablets with food or milk to improve absorption and reduce stomach upset |
Children (Syrup) | – Dose depends on body weight – Example: • 5–14 kg: 1.25 ml per dose • 15–24 kg: 2.5 ml per dose • 25–34 kg: 3.75 ml per dose • >35 kg: Adult dose may apply | Total 6 doses over 3 days | Give syrup twice daily, preferably with food to enhance effectiveness |
Pregnant Women | – Generally, Malarest is not recommended in the first trimester – Can be used cautiously in 2nd and 3rd trimesters under medical supervision | Same 3-day course | Always consult a healthcare provider before use during pregnancy |
Elderly | – Usually the same dosage as adults – Monitor for side effects due to possible decreased metabolism | 3-day course | Adjust dose if significant liver/kidney impairment is present |
Patients with Liver/Kidney Issues | – Dosage adjustment may be necessary – Requires strict medical supervision | Depends on severity | Risk of drug accumulation; the doctor may recommend alternative treatment or a modified dose |
How to Take Malarest
- Take Malarest Tablet with Food:
- Always take Malarest tablets or syrup with food or a light snack. This helps your body absorb the medicine better and reduces the chance of stomach upset.
- Best Time of Day:
- You can take Malarest Tablet any time of day, but try to stick to the prescribed schedule—usually twice daily (morning and evening). Keeping consistent times helps maintain effective medicine levels in your blood.
- Avoid Certain Foods or Drinks:
- Contrary to some myths, you don’t need to avoid milk while taking Malarest. In fact, milk or fatty foods can improve the absorption of the medicine. However, avoid alcohol and grapefruit juice as they may interfere with how the drug works.
- If You Miss a Dose:
- Take the missed dose as soon as you remember.
- If it’s almost time for your next dose, skip the missed one and continue your regular schedule.
- Do not double the dose to make up for a missed one, as this can increase side effects.
- Complete the Full Course:
- Even if you start feeling better, finish all the doses prescribed by your doctor to fully clear the infection and prevent resistance.
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Malarest vs Other Malaria Medicines
Medicine | Key Ingredients | How It Works | Speed of Action | Advantages | Notes |
---|---|---|---|---|---|
Malarest | Artemether + Lumefantrine | Combination therapy: fast parasite kill + long-lasting prevention of recurrence | Fast (symptoms improve in 1-2 days) | Effective in drug-resistant areas; short 3-day course; available in syrup for children | Widely recommended for uncomplicated malaria |
Malarone | Atovaquone + Proguanil | Blocks parasite growth and reproduction | Moderate (symptoms improve in 2-3 days) | Also used for malaria prevention; good for travelers | More expensive; not always first-line treatment |
Chloroquine | Chloroquine phosphate | Kills parasites by interfering with their metabolism | Moderate | Historically widely used; cheap | Many resistant strains now limit effectiveness |
Sulfadoxine-Pyrimethamine | Sulfadoxine + Pyrimethamine | Inhibits parasite DNA synthesis | Slow to moderate | Used in combination therapies and intermittent preventive treatment in pregnancy | Resistance common; often combined with other drugs |
Artemether alone | Artemether | Fast parasite killing | Very fast | Rapid symptom relief | Usually not recommended alone to prevent resistance |
Malarest Tablet Benefits
- Fast-Acting Treatment: Malarest Tablet quickly targets and kills malaria parasites, helping you feel better sooner.
- Reduces Fever and Chills: It effectively lowers common malaria symptoms like fever and chills within the first couple of days.
- Short Treatment Course: Unlike some other malaria medicines, Malarest Tablet requires only a 3-day course, making it easier to complete.
- Prevents Recurrence: The combination of Artemether and Lumefantrine works together to stop the infection from coming back.
- Suitable for All Ages: Available in both tablet and syrup forms, Malarest Tablet is safe and effective for adults and children alike (under doctor supervision).
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Side Effects & Precautions
- Common Side Effects: Headache, dizziness, nausea, and vomiting may occur but are usually mild and temporary.
- Serious Side Effects: Watch for allergic reactions like rash, swelling, difficulty breathing, or irregular heartbeat; seek medical help immediately if these happen.
- Warnings: Malarest Tablet is not meant for malaria prevention (prophylaxis), only for treatment of active infection.
- Use with Caution: People with liver disease or pregnant women (especially in the first trimester) should use Malarest only under strict medical supervision.
- Drug Interactions: Malarest Tablet may interact with antibiotics, anti-seizure medications, and heart medicines, so inform your doctor about all drugs you’re taking.
- Pregnancy & Lactation: Discuss risks and benefits with your healthcare provider before use during pregnancy or breastfeeding.
- Can Malaria Occur Without Fever? Yes, sometimes malaria symptoms can be mild or atypical without a noticeable fever, especially in partially immune individuals.
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FAQs
What is the use of Malarest medicine?
Malarest is used to treat uncomplicated malaria caused by Plasmodium falciparum. It helps kill malaria parasites quickly and reduces symptoms like fever and chills.
What is Mela Rest Tablet used for?
Mela Rest is completely different from Malarest. It is usually a sleep aid or a relaxation medicine, not for malaria treatment. Don’t confuse the two.
Can we take milk during malaria treatment?
Yes, you can drink milk while taking Malarest. In fact, fatty foods or milk can improve the absorption of the medicine, helping it work better.
What if I miss a dose?
Take the missed dose as soon as you remember. If it’s close to the next dose time, skip the missed one. Never double up doses.
Can Malarest cause sleepiness?
Malarest is not known to cause sleepiness as a common side effect. If you feel unusually tired, inform your doctor.
Can malaria occur without fever?
Yes, sometimes malaria infections can be mild or atypical, especially in people with partial immunity, and may not cause noticeable fever.
Is Malarest safe in pregnancy?
Malarest should be used during pregnancy only if prescribed by a doctor, especially avoiding the first trimester unless benefits outweigh risks.
What is the fastest cure for malaria?
Combination therapies like Malarest (Artemether-Lumefantrine) are among the fastest effective treatments for uncomplicated malaria.
How long does it take for Malarest to work?
Most people start feeling better within 24 to 48 hours of starting Malarest treatment.
Can children take Malarest?
Yes, Malarest syrup is specially formulated for children. Dosage depends on the child’s weight and age.
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Conclusion
Malarest is a fast-acting and effective treatment for uncomplicated malaria, suitable for most adults and children (using syrup form). It’s especially helpful if you want a short, reliable course that quickly reduces fever and prevents the infection from coming back.
However, Malarest may not be the best choice for pregnant women in their first trimester, people with severe liver problems, or anyone with a known allergy to its ingredients. If you fall into these groups or have concerns, there are other antimalarial medicines available, like Malarone or Sulfadoxine-Pyrimethamine, which your doctor can recommend.
Always consult a healthcare professional before starting Malarest or any malaria treatment to ensure it’s safe and right for your specific health needs.
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