Allergies are a pervasive health concern across Pakistan, with millions suffering from symptoms triggered by pollen, dust, pollution, and seasonal changes. Finding the right allergy tablet can be a daunting task given the plethora of options available at local pharmacies. This guide is designed to demystify the top five allergy tablets in Pakistan: Baydal, Rigix, Avil, Mexaderm, and Jardin-D. We provide an in-depth analysis of their usage, pricing, side effects, and suitability for different conditions, empowering you to make an informed decision in consultation with your healthcare provider.
In this article, you will learn:
- The definitive breakdown of the top 5 allergy medicines available in Pakistan.
- A clear understanding of how antihistamines work and the difference between types.
- Detailed information on usage, dosage, price, and potential side effects for each tablet.
- Guidance on choosing the right tablet for specific symptoms like skin itching (kharish) and allergic flu.
- Answers to frequently asked questions about safety during pregnancy, daily use, and interactions.
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Table Of Contents
Understanding Allergies and Antihistamines: A Primer
What is an Allergy? A Simple Explanation
An allergy is your body’s immune system overreacting to a typically harmless substance, known as an allergen. When someone with a predisposition to allergies encounters an allergen like pollen, dust mites, or certain foods, their immune system mistakenly identifies it as a dangerous invader. This triggers the release of chemicals, primarily histamine, which leads to the classic symptoms we associate with an allergic reaction.
What are the 7 major allergies?
While there are numerous allergens, seven major categories are commonly recognized. These include:
- Pollen Allergy: From trees, grasses, and weeds, common during spring and fall.
- Dust Mite Allergy: Caused by microscopic insects living in household dust.
- Mold Allergy: Triggered by spores from fungi growing in damp areas.
- Pet Dander Allergy: A reaction to proteins in skin flakes, saliva, and urine of pets like cats and dogs.
- Food Allergy: Reactions to items like nuts, milk, eggs, shellfish, and wheat.
- Insect Sting Allergy: Severe reactions to stings from bees, wasps, or hornets.
- Drug Allergy: An adverse reaction to medications, such as penicillin or certain anti-inflammatory drugs.
What are Antihistamines and How Do They Work?
Antihistamines are a class of drugs primarily used to treat allergy symptoms. They work by blocking the effects of histamine, the key chemical mediator released by your body’s mast cells during an allergic reaction. By occupying the histamine receptors in your body, they prevent histamine from binding to these sites and causing symptoms like sneezing, itching, runny nose, and watery eyes.
First-Generation vs. Second-Generation Antihistamines: What’s the Difference?
Understanding the difference between these two generations is crucial for selecting the right medicine.
- First-Generation Antihistamines (e.g., Avil, Baydal): These are the older class of antihistamines. They are effective but readily cross the blood-brain barrier, which often results in significant drowsiness and sedation. They may also cause dry mouth, dizziness, and blurred vision.
- Second-Generation Antihistamines (e.g., Rigix, Mexaderm, Jardin-D): These are newer formulations designed to be non-drowsy or less drowsy. They do not cross the blood-brain barrier as easily, making them preferable for daily use, for people who need to drive, or for those who operate machinery.
How to Choose the Right Allergy Tablet for You in Pakistan
Selecting the most appropriate allergy medicine requires careful consideration of several factors. A one-size-fits-all approach does not work with antihistamines, as individual response can vary significantly.
Factors to Consider Before Buying an Allergy Medicine
- Your Specific Symptoms: Are you dealing with a runny nose and sneezing (allergic rhinitis), or is severe skin itching (kharish) and hives your main concern? Some tablets are better suited for certain symptoms.
- Drowsiness vs. Non-Drowsy Formulations: Your daily routine is a key deciding factor. If you need to remain alert for work or driving, a second-generation antihistamine is essential. If your allergies are severely disrupting your sleep, a first-generation option at night might be beneficial.
- Underlying Health Conditions: Conditions like high blood pressure, glaucoma, prostate enlargement, or kidney disease can influence which antihistamine is safe for you. Always disclose your full medical history to your doctor.
- Age and Specific Groups: The dosage and safety of allergy tablets differ for children, the elderly, and pregnant or breastfeeding women.
- Cost and Brand Affordability: The price of allergy medicine in Pakistan can vary widely between generic and branded versions. Finding a effective treatment that fits your budget is important for long-term management.
In-Depth Review: Top 5 Allergy Tablets in Pakistan
This section provides a detailed, head-to-head comparison of the five most sought-after allergy tablets in the Pakistani market, analyzing their pros, cons, and ideal use cases.
Rigix (Cetirizine)
Rigix (Cetirizine)
Rigix, containing the active ingredient Cetirizine, is one of the most popular second-generation antihistamines in Pakistan.

What is the use of Rigix tablet?
Rigix, containing the active ingredient Cetirizine, is one of the most popular second-generation antihistamines in Pakistan. It is primarily used for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, runny nose, and itchy/watery eyes. It is also highly effective in treating chronic itching (kharish) and skin conditions like chronic idiopathic urticaria (hives).
Drug Class and Mechanism
Rigix is a second-generation antihistamine. It selectively inhibits H1-receptors, preventing histamine from triggering allergic responses without causing significant drowsiness in most users.
Best For
- General allergic rhinitis and hay fever.
- Chronic skin itching and hives.
- Patients requiring a non-drowsy formula for daily use.
How Fast Does It Work? What is the fastest allergy relief medicine?
Rigix has a relatively rapid onset of action. Symptom relief typically begins within one hour of ingestion, with the peak effect occurring between one to four hours. While not the absolute fastest, it provides a quick and sustained relief for 24 hours.
Usage & Dosage
- The standard adult and children (above 6 years) dose is 10 mg (one tablet) once daily.
- It can be taken with or without food.
- What is the best time of day to take allergy medicine? For Rigix, it can be taken either in the morning or evening, depending on individual response. If you experience slight drowsiness, taking it in the evening is advisable.
Common Side Effects & Risks
- Mild drowsiness or fatigue.
- Dry mouth.
- Headache or dizziness (less common).
Key Considerations & Warnings
- Can I take Rigix daily? Yes, its safety profile makes it suitable for daily, long-term use under medical supervision.
- It is generally considered to have a lower risk profile during pregnancy and breastfeeding compared to first-generation drugs, but a doctor’s consultation is mandatory.
- Use with caution in patients with kidney impairment, as dosage adjustment may be required.
Price Range of Rigix in Pakistan
The price for a strip of 10 Rigix tablets typically Pkr. 110, making it an affordable and accessible option.
Verdict: Who should use it?
Rigix (Cetirizine) is an excellent all-rounder for most adults and children suffering from common allergies and skin itching. It is a go-to choice for those seeking effective, 24-hour relief without pronounced drowsiness.
Avil (Pheniramine Maleate)
Avil (Pheniramine Maleate)
Avil, containing Pheniramine Maleate, is a potent and fast-acting first-generation antihistamine.

Is Avil Tablet good for allergy?
Yes, Avil, containing Pheniramine Maleate, is a potent and fast-acting first-generation antihistamine. It is highly effective for providing rapid relief from acute allergic reactions, severe itching, and allergic conjunctivitis. However, its use is often limited by its strong sedative properties.
Drug Class and Mechanism
Avil is a first-generation antihistamine. It acts on H1-receptors in the body and the central nervous system, which is responsible for its potent anti-allergic and sedative effects.
Best For
- Acute and severe allergic episodes.
- Providing relief from intense, uncontrollable itching.
- Situations where a sedative effect is desirable.
How Fast Does It Work? What is the fastest medicine for allergies?
Avil is known for its very fast onset of action. Many users report feeling relief from symptoms within 30 to 60 minutes, making it one of the faster-acting options available over-the-counter.
Usage & Dosage
- The common adult dose is 22.5 mg to 45 mg (half to one tablet) two to three times a day.
- It is crucial not to exceed the recommended dosage due to the risk of increased side effects.
Common Side Effects & Risks
- Pronounced drowsiness and sedation.
- Dizziness and loss of coordination.
- Dry mouth, blurred vision, and constipation.
Key Considerations & Warnings
- Do not drive or operate heavy machinery after taking Avil.
- It is not recommended for daily long-term use for allergy management due to its side effect profile.
- Avoid concurrent use with alcohol or other central nervous system depressants.
Price Range of Avil in Pakistan
Avil is very economical, with a strip of 10 tablets costing approximately PKR 70.
Verdict: Who should use it?
Avil is a powerful tool for short-term, severe symptom relief. It is best used intermittently and when the user can remain at home and rest due to its high potential for causing drowsiness.
Baydal (Chlorpheniramine Maleate)
Baydal (Chlorpheniramine Maleate)
Baydal’s active ingredient is Chlorpheniramine Maleate, a first-generation antihistamine. It is widely used for relieving symptoms of allergic conditions like rhinitis, conjunctivitis, and skin allergies.

What is Baydal used for?
Baydal’s active ingredient is Chlorpheniramine Maleate, a first-generation antihistamine. It is widely used for relieving symptoms of allergic conditions like rhinitis, conjunctivitis, and skin allergies. It is also a common component in over-the-counter cold and flu remedies due to its ability to dry up nasal secretions.
Drug Class and Mechanism
As a first-generation antihistamine, Baydal works by antagonizing H1-receptors, providing relief from allergy symptoms but with a significant risk of central nervous system depression.
Best For
- Managing symptoms of allergic rhinitis and skin rashes.
- As a best anti allergy for flu in Pakistan, often found in combination cold tablets.
How Fast Does It Work?
Baydal starts to work within 30 to 60 minutes after oral administration, providing relatively quick relief.
Usage & Dosage
- The usual adult dose is 4 mg every 4 to 6 hours, not to exceed 24 mg in 24 hours.
Common Side Effects & Risks
- Drowsiness, sleepiness, and dizziness.
- Dry mouth and blurred vision.
- Gastrointestinal upset.
Key Considerations & Warnings
- Similar to Avil, it causes significant sedation and impairs alertness.
- Not ideal for long-term, daily control of chronic allergies.
- Often marketed for multi-symptom cold relief, so check the formulation to avoid double-dosing when taking other cold medicines.
Price Range of Baydal in Pakistan
Baydal is one of the most cost-effective antihistamines, with a price of PKR 55 per strip.
Verdict: Who should use it?
Baydal is a budget-friendly option for temporary relief from allergy and cold-like symptoms, best used when sedation is not a concern.
Mexaderm (Loratadine)
Mexaderm (Loratadine)
Mexaderm is a common brand of Loratadine available in Pakistan. Loratadine is a second-generation antihistamine renowned for its non-drowsy profile.

What is the brand name of Loratadine in Pakistan?
Mexaderm is a common brand of Loratadine available in Pakistan. Loratadine is a second-generation antihistamine renowned for its non-drowsy profile.
Drug Class and Mechanism
Mexaderm is a second-generation antihistamine. It selectively blocks peripheral H1-receptors, offering relief from allergies without crossing the blood-brain barrier to a significant degree, thereby minimizing drowsiness.
Best For
- 24-hour non-drowsy relief from seasonal allergies.
- Patients who experience drowsiness with other antihistamines like Cetirizine.
- Managing chronic skin allergies without sedation.
How Fast Does It Work?
Mexaderm’s onset of action is slightly slower than some others. It may take 1 to 3 hours to begin working, but its effects are long-lasting, providing full 24-hour coverage.
Usage & Dosage
- The standard dose for adults and children over 6 years is 10 mg (one tablet) once daily.
Common Side Effects & Risks
- It is generally very well-tolerated.
- Rare side effects may include headache, fatigue, or dry mouth.
Key Considerations & Warnings
- A top choice for individuals who need to remain completely alert throughout the day.
- Taking it on an empty stomach may lead to faster absorption.
Price Range of Mexaderm in Pakistan
A strip of 10 Mexaderm tablets is typically PKR 140.
Verdict: Who should use it?
Mexaderm (Loratadine) is the ideal choice for students, drivers, and working professionals who require effective, all-day allergy relief without any compromise on mental alertness.
Jardin-D (Levocetirizine)
Jardin-D (Levocetirizine)
Jardin-D contains Levocetirizine, which is an active enantiomer of Cetirizine.

What is the new allergy medicine?
Jardin-D contains Levocetirizine, which is an active enantiomer of Cetirizine. It is often considered a refined and potent version, offering a faster onset and potentially stronger effect with a similarly low risk of drowsiness.
Drug Class and Mechanism
Jardin-D is a second-generation antihistamine. It is the R-enantiomer of cetirizine and has a higher affinity for H1-receptors, which is why it is considered more potent at a lower dose.
Best For
- Powerful and fast-acting relief for persistent allergic rhinitis.
- Severe chronic itching and urticaria (hives) that does not respond adequately to other antihistamines.
How Fast Does It Work? What allergy medicine works in 30 minutes?
Jardin-D has a very rapid onset. It can start relieving symptoms in as little as 30 to 60 minutes, making it one of the fastest-acting second-generation antihistamines available.
Usage & Dosage
- The recommended dose for adults and children over 6 years is 5 mg (one tablet) once daily.
Common Side Effects & Risks
- Side effects are similar to cetirizine but may be less frequent; these include mild drowsiness, headache, and dry mouth.
Key Considerations & Warnings
- It is a potent option for those who have not found sufficient relief with Loratadine or even Cetirizine.
- Due to its potency, it is essential to stick to the prescribed 5 mg dose.
Price Range of Jardin-D in Pakistan
As a newer and more potent drug, Jardin-D is priced higher, usually PKR 250 per strip of 10 tablets.
Verdict: Who should use it?
Jardin-D (Levocetirizine) is for those who need a stronger, faster, and more potent antihistamine effect without the baggage of first-generation sedation. It is a premium choice for stubborn allergy symptoms.
Comprehensive Comparison and FAQs
Head-to-Head Comparison Table
| Feature | Rigix (Cetirizine) | Avil (Pheniramine) | Baydal (Chlorpheniramine) | Mexaderm (Loratadine) | Jardin-D (Levocetirizine) |
|---|---|---|---|---|---|
| Generic Name | Cetirizine | Pheniramine Maleate | Chlorpheniramine Maleate | Loratadine | Levocetirizine |
| Generation | Second | First | First | Second | Second |
| Best For | All-round allergies & itching | Acute, severe symptoms | Allergies & cold symptoms | Non-drowsy daily relief | Potent, fast relief for stubborn symptoms |
| Drowsiness | Low to Moderate | High | High | Very Low | Low |
| Dosage | 10 mg once daily | 22.5-45 mg, 2-3 times/day | 4 mg every 4-6 hrs | 10 mg once daily | 5 mg once daily |
| Price (PKR) | 80 – 120 | 40 – 70 | 30 – 60 | 90 – 140 | 150 – 220 |
Frequently Asked Questions About Allergy Tablets in Pakistan
Which allergy tablet works best?
There is no single “best” allergy tablet for everyone. The most effective tablet depends on your specific symptoms, your body’s individual response, and your lifestyle needs. For general, non-drowsy daily use, Rigix (Cetirizine) or Mexaderm (Loratadine) are excellent starting points. For fast, powerful relief where drowsiness is not a concern, Avil can be very effective. Jardin-D is often the most potent second-generation option.
What’s the strongest allergy tablet?
In terms of pharmacological potency, Jardin-D (Levocetirizine) is considered one of the strongest second-generation antihistamines. Among first-generation options, Avil (Pheniramine) is very strong and fast-acting. “Strongest” can refer to either the intensity of the effect or the speed of onset, and both these tablets excel in their respective categories.
Can I take allergy tablets daily?
Yes, but only certain types. Second-generation antihistamines like Rigix (Cetirizine), Mexaderm (Loratadine), and Jardin-D (Levocetirizine) are designed and deemed safe for daily use to manage chronic allergy symptoms. First-generation antihistamines like Avil and Baydal are not recommended for long-term daily use due to their side effect profile, particularly sedation and potential cognitive impairment.
What is the fastest way to stop skin allergies?
The fastest way to stop a skin allergy (kharish) involves a multi-pronged approach:
- Immediately avoid the allergen if it is known.
- Take a fast-acting oral antihistamine like Avil or Jardin-D.
- Apply a cool, damp cloth or take a cool bath to soothe the skin.
- Use a fragrance-free moisturizer to repair the skin barrier.
- For severe cases, a doctor may prescribe a topical corticosteroid cream for rapid local relief.
Which allergy medicine is safe during pregnancy?
This is a critical question that must be addressed by a healthcare professional. No antihistamine is 100% proven safe during pregnancy. However, some, like Loratadine (Mexaderm) and Cetirizine (Rigix), are often considered to have a more favorable safety profile based on existing data and are sometimes recommended when the benefits outweigh the risks. Self-medication during pregnancy is strongly discouraged.
What allergy medicine is safe for high blood pressure?
Most plain second-generation antihistamines like Loratadine (Mexaderm), Cetirizine (Rigix), and Fexofenadine are generally considered safe for individuals with high blood pressure. The critical thing to avoid are combination cold and allergy tablets that contain decongestants like pseudoephedrine or phenylephrine, as these can raise blood pressure. Always choose single-ingredient antihistamines and consult your doctor.
Can I take two allergy pills? / How much allergy medicine can I take in 24 hours?
You should never exceed the recommended dosage listed on the product packaging or prescribed by your doctor. Taking two pills of the same antihistamine at once or exceeding the 24-hour limit can lead to an overdose, increasing the risk of severe side effects like extreme drowsiness, seizures, or heart problems. If one pill is not effective, consult a doctor for an alternative or stronger prescription.
Special Focus: Skin Allergies and Itching (Kharish) in Pakistan
What is the best treatment for skin allergies?
The best treatment for skin allergies is a comprehensive strategy that includes avoidance, skincare, and medication. Identifying and avoiding the trigger is the first and most crucial step. A consistent skincare routine using gentle, hypoallergenic products helps restore the skin barrier. Medically, oral antihistamines are the cornerstone of systemic treatment for relieving itch.
Which allergy pill is best for itching?
For relieving skin itching (kharish), the best pills are those that strongly block the histamine pathways responsible for itch.
- For rapid, severe itching: Avil (Pheniramine) is very effective but causes drowsiness.
- For daily, non-sedating control of chronic itch: Jardin-D (Levocetirizine) is often the most potent, followed by Rigix (Cetirizine). These are excellent for conditions like chronic urticaria.
What is the strongest antihistamine for itchy skin?
Among second-generation antihistamines, Levocetirizine (found in Jardin-D) is often regarded as the strongest for suppressing itchy skin. Among all categories, first-generation drugs like Hydroxyzine (a prescription drug) or high-dose Pheniramine (Avil) are very strong but come with significant sedation.
How do I treat a skin allergy? A Step-by-Step Guide
- Identify and Avoid: Try to pinpoint the cause (e.g., new soap, detergent, food, fabric) and eliminate contact.
- Soothe the Skin: Apply a cool, wet compress to the affected area for 15-30 minutes several times a day.
- Moisturize Liberally: Use a thick, fragrance-free moisturizer like petroleum jelly or ceramide-based creams to protect the skin.
- Take an Oral Antihistamine: Use a suitable antihistamine from the list above to control the itch from within.
- Use a Topical Cream: For persistent rash, a doctor may recommend a topical steroid cream like hydrocortisone for a short period.
Important Safety Information and Warnings
When to See a Doctor Instead of Self-Medicating
Self-medication with over-the-counter allergy tablets has its limits. You must consult a doctor if you experience:
- Symptoms that are severe or do not improve after a week of self-treatment.
- Difficulty breathing, wheezing, or tightness in the chest.
- Swelling of the lips, tongue, throat, or face.
- Signs of a skin infection, such as increased pain, pus, or fever.
- You are pregnant, breastfeeding, or treating a young child.
The Danger of Self-Medication and Misdiagnosis
Using allergy tablets can mask the symptoms of a more serious condition. What seems like an allergy could be a sinus infection, asthma, or another medical issue that requires a different treatment. A proper diagnosis is essential for effective and safe management.
Conclusion
Navigating the world of allergy tablets in Pakistan requires a balance of understanding your symptoms, your body’s response, and your daily life demands. From the rapid relief of Avil to the non-drowsy endurance of Mexaderm and the potent action of Jardin-D, there is a solution for nearly every type of allergy sufferer. Use this guide as a detailed roadmap to have an informed discussion with your pharmacist or doctor. By choosing wisely, you can effectively manage your allergies and significantly improve your quality of life.

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