// Initialize jsPDF const { jsPDF } = window.jspdf; // Real-time slider update document.getElementById(‘noduleSize’).addEventListener(‘input’, function() { document.getElementById(‘noduleSizeValue’).textContent = this.value; });function calculateRisk() { // Validate required fields const name = document.getElementById(‘name’).value; const age = document.getElementById(‘age’).value; if (!name || !age) { alert(‘Please enter your name and age to calculate risk.’); return; } if (age 120) { alert(‘Please enter a valid age between 1 and 120.’); return; }// Gather all risk factors const riskFactors = { name: name, age: parseInt(age), gender: document.getElementById(‘gender’).value, noduleSize: parseInt(document.getElementById(‘noduleSize’).value), noduleConsistency: parseInt(document.getElementById(‘noduleConsistency’).value), noduleCalcifications: parseInt(document.getElementById(‘noduleCalcifications’).value), noduleVascularity: parseInt(document.getElementById(‘noduleVascularity’).value), familyHistory: parseInt(document.getElementById(‘familyHistory’).value), radiation: parseInt(document.getElementById(‘radiation’).value), thyroidDisease: parseInt(document.getElementById(‘thyroidDisease’).value), tsh: parseFloat(document.getElementById(‘tsh’).value) || 0, thyroglobulin: parseFloat(document.getElementById(‘thyroglobulin’).value) || 0, calcitonin: parseFloat(document.getElementById(‘calcitonin’).value) || 0, symptoms: { hoarseness: document.getElementById(‘symptomHoarseness’).checked ? 1 : 0, swallowing: document.getElementById(‘symptomSwallowing’).checked ? 1 : 0, breathing: document.getElementById(‘symptomBreathing’).checked ? 2 : 0, neckMass: document.getElementById(‘symptomNeckMass’).checked ? 1 : 0, pain: document.getElementById(‘symptomPain’).checked ? 1 : 0 } };// Calculate risk score (comprehensive algorithm) let riskScore = 0; // Age adjustment (U-shaped risk curve) if (riskFactors.age 60) { riskScore += 5; } // Gender adjustment if (riskFactors.gender === ‘female’) { riskScore += 3; } // Nodule characteristics riskScore += riskFactors.noduleSize * 0.5; // 0-25 points riskScore += riskFactors.noduleConsistency * 2; riskScore += riskFactors.noduleCalcifications; riskScore += riskFactors.noduleVascularity * 1.5; // Medical history riskScore += riskFactors.familyHistory; riskScore += riskFactors.radiation; riskScore += riskFactors.thyroidDisease; // Lab values if (riskFactors.tsh > 4.5) { riskScore += Math.min((riskFactors.tsh – 4.5) * 0.5, 10); } if (riskFactors.calcitonin > 10) { riskScore += Math.min(riskFactors.calcitonin * 0.1, 15); } // Symptoms riskScore += riskFactors.symptoms.hoarseness * 3; riskScore += riskFactors.symptoms.swallowing * 2; riskScore += riskFactors.symptoms.breathing; riskScore += riskFactors.symptoms.neckMass * 2; riskScore += riskFactors.symptoms.pain; // Cap at 100 riskScore = Math.min(Math.round(riskScore), 100); // Display results document.getElementById(‘results’).style.display = ‘block’; document.getElementById(‘riskScore’).textContent = riskScore; document.getElementById(‘socialSharing’).style.display = ‘flex’; // Position risk indicator const indicator = document.getElementById(‘riskIndicator’); indicator.style.left = `${riskScore}%`; // Interpretation and recommendations const interpretation = document.getElementById(‘riskInterpretation’); const recommendations = document.getElementById(‘recommendations’); if (riskScore < 20) { interpretation.innerHTML = 'LOW RISK – Your calculated risk of thyroid cancer is low.’; recommendations.innerHTML = `

Recommendations:

• Routine thyroid monitoring as part of regular health check-ups
• Consider thyroid ultrasound if nodule >1cm
• Follow-up with your doctor if you notice any changes

`; } else if (riskScore < 50) { interpretation.innerHTML = 'MODERATE RISK – Your calculated risk of thyroid cancer warrants further evaluation.’; recommendations.innerHTML = `

Recommendations:

• Consult with an endocrinologist or thyroid specialist
• Thyroid ultrasound recommended
• Consider fine needle aspiration (FNA) biopsy if nodule >1cm
• Monitor for any symptom changes

`; } else { interpretation.innerHTML = ‘HIGH RISK – Your calculated risk of thyroid cancer is high and requires prompt medical attention.’; recommendations.innerHTML = `

Recommendations:

• Immediate consultation with a thyroid specialist
• Diagnostic thyroid ultrasound and FNA biopsy recommended
• Consider additional testing (CT scan, molecular testing)
• Regular monitoring until evaluation is complete

`; } // Scroll to results document.getElementById(‘results’).scrollIntoView({ behavior: ‘smooth’ }); }function generatePDF() { const doc = new jsPDF(); // Report Header doc.setFontSize(16); doc.setTextColor(42, 100, 150); doc.text(“THYROID CANCER RISK ASSESSMENT REPORT”, 105, 20, null, null, ‘center’); doc.setFontSize(10); doc.setTextColor(100, 100, 100); doc.text(`Report generated on: ${new Date().toLocaleString()}`, 105, 28, null, null, ‘center’); doc.setDrawColor(42, 100, 150); doc.setLineWidth(0.5); doc.line(20, 32, 190, 32); // Patient Information doc.setFontSize(12); doc.setTextColor(0, 0, 0); doc.text(“PATIENT INFORMATION”, 20, 42); doc.setFontSize(10); doc.text(`Name: ${document.getElementById(‘name’).value}`, 20, 50); doc.text(`Age: ${document.getElementById(‘age’).value}`, 20, 56); doc.text(`Gender: ${document.getElementById(‘gender’).value}`, 20, 62); // Risk Score Summary doc.setFontSize(12); doc.text(“RISK ASSESSMENT SUMMARY”, 20, 76); doc.setFontSize(36); const riskScore = document.getElementById(‘riskScore’).textContent; doc.setTextColor(42, 100, 150); doc.text(`${riskScore}/100`, 105, 90, null, null, ‘center’); doc.setFontSize(10); doc.setTextColor(0, 0, 0); doc.text(document.getElementById(‘riskInterpretation’).textContent, 105, 100, null, null, ‘center’); // Risk Meter Visualization doc.setDrawColor(200, 200, 200); doc.setLineWidth(0.5); doc.line(20, 110, 190, 110); // Clinical Parameters doc.setFontSize(12); doc.text(“CLINICAL PARAMETERS”, 20, 120); let yPos = 128; const inputs = [ { id: ‘noduleSize’, label: ‘Nodule Size (mm)’ }, { id: ‘noduleConsistency’, label: ‘Nodule Consistency’ }, { id: ‘noduleCalcifications’, label: ‘Nodule Calcifications’ }, { id: ‘noduleVascularity’, label: ‘Nodule Vascularity’ }, { id: ‘familyHistory’, label: ‘Family History’ }, { id: ‘radiation’, label: ‘Radiation Exposure’ }, { id: ‘thyroidDisease’, label: ‘Thyroid Disease History’ }, { id: ‘tsh’, label: ‘TSH Level (mIU/L)’ }, { id: ‘calcitonin’, label: ‘Calcitonin Level (pg/mL)’ } ]; inputs.forEach((input, index) => { const col = index % 2 === 0 ? 20 : 110; if (index % 2 === 0 && index !== 0) yPos += 8; const element = document.getElementById(input.id); let value = element.value; if (element.tagName === ‘SELECT’) { value = element.options[element.selectedIndex].text; } doc.text(`${input.label}: ${value}`, col, yPos); if (index % 2 !== 0) yPos += 8; }); // Symptoms yPos += 8; doc.text(“Symptoms Present:”, 20, yPos); yPos += 8; const symptoms = [ { id: ‘symptomHoarseness’, label: ‘Hoarseness’ }, { id: ‘symptomSwallowing’, label: ‘Difficulty swallowing’ }, { id: ‘symptomBreathing’, label: ‘Difficulty breathing’ }, { id: ‘symptomNeckMass’, label: ‘Visible neck mass’ }, { id: ‘symptomPain’, label: ‘Neck pain’ } ]; let symptomsPresent = symptoms.filter(s => document.getElementById(s.id).checked) .map(s => s.label) .join(‘, ‘); if (!symptomsPresent) symptomsPresent = “None reported”; doc.text(symptomsPresent, 20, yPos, { maxWidth: 170 }); yPos += 16; // Recommendations doc.setFontSize(12); doc.text(“RECOMMENDATIONS”, 20, yPos); yPos += 8; const recommendations = document.getElementById(‘recommendations’).querySelector(‘ul’); const recommendationItems = Array.from(recommendations.querySelectorAll(‘li’)).map(li => li.textContent); recommendationItems.forEach(item => { if (yPos > 250) { doc.addPage(); yPos = 20; } doc.text(`• ${item}`, 25, yPos, { maxWidth: 160 }); yPos += 8; }); // Footer doc.setFontSize(8); doc.setTextColor(100, 100, 100); doc.text(“This report was generated by the Thyroid Cancer Risk Calculator from DoseWay”, 105, 285, null, null, ‘center’); doc.text(“For questions or concerns, contact: support@doseway.com | WhatsApp: +92318-6144650”, 105, 290, null, null, ‘center’); // Save PDF doc.save(`Thyroid_Risk_Assessment_${document.getElementById(‘name’).value.replace(‘ ‘, ‘_’)}.pdf`); } // Social sharing functions function shareOnFacebook() { const url = encodeURIComponent(window.location.href); const text = encodeURIComponent(`My thyroid cancer risk assessment score is ${document.getElementById(‘riskScore’).textContent}/100. Check yours!`); window.open(`https://www.facebook.com/sharer/sharer.php?u=${url}&quote=${text}`, ‘_blank’); } function shareOnTwitter() { const text = encodeURIComponent(`My thyroid cancer risk score: ${document.getElementById(‘riskScore’).textContent}/100. Calculate yours at`); const url = encodeURIComponent(window.location.href); window.open(`https://twitter.com/intent/tweet?text=${text}&url=${url}`, ‘_blank’); } function shareOnLinkedIn() { const url = encodeURIComponent(window.location.href); window.open(`https://www.linkedin.com/shareArticle?mini=true&url=${url}`, ‘_blank’); } function shareOnWhatsApp() { const text = encodeURIComponent(`My thyroid cancer risk assessment score is ${document.getElementById(‘riskScore’).textContent}/100. Check yours here: ${window.location.href}`); window.open(`https://wa.me/?text=${text}`, ‘_blank’); }

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Thyroid Cancer Risk Calculator: Thyroid Cancer Risk Assessment

Understanding Thyroid Cancer

Thyroid cancer develops in the thyroid gland, a butterfly-shaped organ at the base of the neck responsible for hormone regulation. Common types include:

• Papillary carcinoma (most common)
• Follicular thyroid cancer
• Medullary thyroid cancer
• Anaplastic thyroid cancer (rare, aggressive)

Early detection through thyroid nodule evaluation and risk stratification significantly improves outcomes.

Key Terms Explained

Semantic Terms Related to Thyroid Cancer

• Thyroid Nodules: Abnormal growths in the thyroid gland.
• TSH Levels: Thyroid-stimulating hormone, critical for thyroid function.
• Fine-Needle Aspiration (FNA): Diagnostic procedure for suspicious nodules.
• Radiation Exposure: Linked to increased papillary carcinoma risk.
• Lymph Node Metastasis: Spread of cancer to lymph nodes.

How Our Thyroid Cancer Risk Calculator Works

This tool evaluates critical risk factors using evidence-based algorithms:

Factors Analyzed

• Demographics:
  • Age (risk increases with age)
  • Gender (women are 3x more likely to develop thyroid cancer)
• Clinical Markers:
  • Thyroid Nodule Size: Larger nodules (>1 cm) require closer monitoring.
  • Family History: Genetic predisposition (e.g., MEN2 syndrome).
  • Radiation Exposure: Childhood exposure increases risk.
  • TSH Levels: Elevated TSH correlates with malignancy risk.

Interpreting Your Results

The calculator generates a risk score (0-100) with color-coded guidance:

Risk Level	Score Range	Action
Low	0-20	Annual ultrasound monitoring
Moderate	21-50	Consult an endocrinologist for FNA biopsy
High	51-100	Immediate specialist referral & diagnostic imaging

Example Scenario:

A 45-year-old woman with a 2.5 cm nodule, elevated TSH (6.2 mIU/L), and childhood radiation exposure would receive a high-risk score, triggering urgent follow-up.

Why Use This Calculator?

• Early Detection: Identifies asymptomatic risks.
• Personalized Insights: Tailored recommendations based on clinical guidelines.
• PDF Report: Downloadable clinical summary for healthcare providers.

Thyroid Cancer Prevention Strategies

• Regular Palpation: Self-exam for neck lumps.
• Ultrasound Screening: Recommended for high-risk groups.
• Iodine-Rich Diet: Supports thyroid health.

FAQs