Description
Wilgesic Tablet 450mg/35mg is a trusted prescription-only medication formulated to provide effective relief from moderate to severe pain associated with muscle spasms and musculoskeletal conditions. This potent combination therapy targets pain through a dual-action mechanism, addressing both the sensation of pain and the muscular tension that often accompanies it. It is a go-to solution for individuals suffering from painful muscular skeletal disorders, offering a path back to comfort and mobility.
This comprehensive guide will detail everything you need to know about Wilgesic tablets. Here’s a brief overview of what makes this product a reliable choice for pain management:
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✅ Dual-Action Formula: Combines a pain reliever with a muscle relaxant for comprehensive relief.
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✅ Targeted Relief: Specifically effective for pain caused by muscle spasms, strains, and injuries.
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✅ Trusted Manufacturing: Produced under strict Good Manufacturing Practice (GMP) standards ensuring quality and consistency.
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✅ Clear Dosage Regimen: Provides structured usage guidelines for safe and effective treatment.
What is Wilgesic Tablet and How Does it Work?
Wilgesic is a combination pharmaceutical product containing two active ingredients: Paracetamol (450mg) and Orphenadrine Citrate (35mg). This formulation is designed to work synergistically. Paracetamol, also known as acetaminophen, is a widely used analgesic (pain reliever) and antipyretic (fever reducer) that works primarily in the central nervous system to elevate the pain threshold. Orphenadrine Citrate is a skeletal muscle relaxant that acts centrally in the brain and spinal cord to relieve muscle spasms and associated pain without directly affecting muscle fibers. Together, they provide more effective relief for conditions where pain and muscle stiffness are intertwined than either component could alone.
What are the Primary Uses and Key Features of Wilgesic?
Primary Therapeutic Uses of Wilgesic 450mg/35mg
Wilgesic tablets are prescribed for the short-term management of acute, painful musculoskeletal conditions. Its primary uses include:
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Relief of pain and muscle spasm associated with backaches, including lumbago and sciatica.
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Management of discomfort from neck pain (cervical spondylosis) and shoulder pain.
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Alleviating pain from muscle strains, sprains, and injuries.
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Adjunctive therapy in conditions like fibromyalgia and arthritis where muscular pain is a significant component.
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Post-operative pain relief following orthopedic procedures.
Key Features and Benefits of This Combination Analgesic
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Synergistic Pain Management:Â The combination addresses both nociceptive pain and muscular hypertonia, breaking the pain-spasm-pain cycle.
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Rapid Onset of Action:Â Provides relatively quick relief, helping patients resume daily activities.
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Non-Steroidal Alternative:Â Offers an option for patients who cannot tolerate NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) due to gastric or renal concerns.
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Improved Functional Outcomes:Â By reducing muscle spasm, it can help improve range of motion and facilitate physiotherapy.
What Are the Active Ingredients in Wilgesic and Their Benefits?
Detailed Ingredient Breakdown:
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Paracetamol (Acetaminophen) 450mg:Â A central analgesic and antipyretic. It inhibits the synthesis of prostaglandins in the central nervous system, reducing the perception of pain and helping to lower fever. It is well-tolerated by most patients when used at recommended doses.
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Orphenadrine Citrate 35mg:Â A central-acting anticholinergic muscle relaxant. It blocks muscarinic receptors and neuronal reuptake in the brainstem and spinal cord, reducing the reflex activity of skeletal muscles and relieving spasms without impairing muscle strength.
How Should I Use Wilgesic Tablets Correctly?
Directions for Safe and Effective Use
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Administration:Â Take this medicine by mouth with a full glass of water. It can be taken with or without food, but taking it with food may help prevent potential stomach upset.
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Swallow Whole:Â Do not crush, chew, or break the tablet unless advised by your doctor.
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Consistency:Â Try to take your doses at the same times each day to maintain a consistent level of medicine in your body.
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Duration:Â Use this medication exactly as prescribed by your healthcare professional. Do not use it for longer than the recommended period.
What is the Recommended Dosage for Wilgesic 450mg/35mg?
Dosage must be individualized by a physician based on the patient’s condition and response. The typical adult dosage is:
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Standard Adult Dose:Â One tablet three times a day.
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Maximum Daily Dose:Â Do not exceed three tablets (total of 1350mg Paracetamol / 105mg Orphenadrine Citrate) in 24 hours.
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Elderly Patients:Â A lower dose may be recommended due to increased sensitivity and potential for side effects.
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Duration of Therapy:Â Usually prescribed for short-term use (not exceeding 5-7 days continuously for musculoskeletal pain) unless directed by a doctor. Long-term use requires medical supervision.
What Precautions and Warnings Should I Be Aware Of?
Important Safety Information and Contraindications
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Medical History Disclosure:Â Inform your doctor if you have a history of liver disease, kidney impairment, glaucoma, prostate enlargement, urinary retention, myasthenia gravis, or heart problems.
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Allergies:Â Do not take if you have a known hypersensitivity to Paracetamol, Orphenadrine, or any other component of the formulation.
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Alcohol Warning:Â Avoid alcohol consumption while taking this medication. Alcohol can increase the risk of liver damage from Paracetamol and potentiate the drowsiness caused by Orphenadrine.
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Pregnancy and Lactation:Â Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The benefits and risks must be carefully evaluated.
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Driving and Operating Machinery:Â Orphenadrine can cause dizziness, drowsiness, and blurred vision. Do not drive or engage in hazardous activities until you know how this medicine affects you.
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Drug Interactions:Â Inform your doctor about all other medicines you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Significant interactions can occur with other anticholinergic drugs, sedatives, antidepressants, and certain antibiotics.
What Are the Possible Side Effects of Wilgesic?
While not everyone experiences side effects, it is important to be aware of potential reactions. These are usually mild and may subside as your body adjusts.
Common Side Effects:
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Dry mouth
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Drowsiness, dizziness
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Blurred vision
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Nausea, gastrointestinal discomfort
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Constipation
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Mild headache
Less Common but Serious Side Effects (Seek Medical Attention):
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Signs of an allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
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Symptoms of liver problems: persistent nausea/vomiting, loss of appetite, severe stomach/abdominal pain, yellowing of eyes/skin, dark urine.
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Difficulty urinating or painful urination.
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Fast/irregular heartbeat.
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Mental/mood changes (e.g., confusion, hallucinations).
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Unusual tiredness, signs of infection (e.g., fever, persistent sore throat).
How Should I Store Wilgesic Tablets?
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Temperature: Store below 25°C, in a cool, dry place.
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Moisture & Light:Â Protect from light and moisture. Keep the tablets in their original blister pack until use.
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Accessibility:Â Keep out of reach and sight of children and pets.
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Disposal:Â Do not use after the expiry date printed on the pack. Dispose of unused medicine properly; do not flush down the toilet or throw in household trash. Consult your pharmacist for safe disposal methods.
Who Manufactures Wilgesic Tablets?
Wilgesic tablets are manufactured by Wilshire Laboratories (Pvt) Ltd, a reputable pharmaceutical company committed to producing high-quality, affordable medicines. The company operates in compliance with stringent Good Manufacturing Practice (GMP) guidelines set by regulatory authorities, ensuring that every batch meets rigorous standards of purity, potency, and safety. Their facilities are subject to regular inspections to uphold these quality benchmarks.
What Are the Comprehensive Benefits of Using Wilgesic for Pain Relief?
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Dual-Mechanism Action:Â Provides a two-pronged attack on pain by combining an analgesic with a muscle relaxant, which is often more effective for musculoskeletal pain than a simple painkiller.
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Reduces Muscle Stiffness and Spasm:Â Directly targets muscle hypertonia, improving flexibility and reducing the risk of secondary pain from compensatory postures.
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Facilitates Recovery and Rehabilitation:Â By alleviating pain and spasm, it allows patients to participate more effectively in physiotherapy and rehabilitation exercises, speeding up recovery.
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Improves Sleep Quality:Â Chronic pain and muscle spasms can severely disrupt sleep. Effective management of these symptoms can lead to better rest, which is crucial for healing.
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Enhances Daily Functioning:Â Helps restore mobility and the ability to perform activities of daily living, thereby improving overall quality of life during recovery from injury or acute flare-ups of chronic conditions.
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Well-Established Safety Profile:Â When used as directed under medical supervision, the combination has a known and manageable side effect profile.
How Does Wilgesic Compare to Other Pain Relief Medications?
The following comparison highlights key differences to inform discussions with healthcare providers.
Wilgesic vs. Common Pain Relief Alternatives
| Feature | Wilgesic (Paracetamol + Orphenadrine) | NSAIDs (e.g., Ibuprofen, Diclofenac) | Plain Paracetamol | Other Muscle Relaxants (e.g., Cyclobenzaprine) |
|---|---|---|---|---|
| Primary Action | Analgesic + Muscle Relaxant | Anti-inflammatory, Analgesic, Antipyretic | Analgesic & Antipyretic | Muscle Relaxant |
| Best For | Pain WITH muscle spasm (backache, strain) | Pain WITH inflammation (arthritis, tendonitis) | Mild to moderate pain, Fever | Muscle spasm with minimal pain |
| GI Side Effects | Lower risk (unless with food issues) | Higher risk (ulcers, bleeding) | Very low risk | Moderate risk (dry mouth, constipation) |
| Key Consideration | Drowsiness common; avoid alcohol. | Not suitable for kidney/heart issues; can increase BP. | Liver risk in overdose. | Often causes significant sedation. |
Frequently Asked Questions About Wilgesic 450mg/35mg
Is Wilgesic a narcotic or addictive painkiller?
No, Wilgesic is not a narcotic (opioid). Its ingredients, Paracetamol and Orphenadrine, are not classified as addictive substances. However, psychological dependence is rare and physical dependence is not expected when used as prescribed for short durations.
Can I take Wilgesic for a headache or menstrual cramps?
Wilgesic is not typically a first-line treatment for common headaches or primary dysmenorrhea (menstrual cramps). It is specifically formulated for pain associated with muscle spasms. For headaches or menstrual pain, simpler analgesics like plain paracetamol or NSAIDs are usually recommended. Always consult a doctor.
How long does it take for Wilgesic to start working?
You may begin to feel the effects of pain relief and muscle relaxation within 30 to 60 minutes after taking a dose. The full therapeutic effect is usually achieved with consistent use over a few days as prescribed.
Can I take Wilgesic with other over-the-counter cold and flu medicines?
You must exercise extreme caution. Many over-the-counter cold, flu, and multi-symptom relief products contain paracetamol. Taking Wilgesic with these can easily lead to a paracetamol overdose, which can cause severe liver damage. Always check labels and inform your doctor or pharmacist of all products you are using.
What should I do if I miss a dose of Wilgesic?
If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Is it safe to use Wilgesic for long-term chronic back pain?
Wilgesic is generally recommended for short-term management of acute painful musculoskeletal conditions. Long-term use of muscle relaxants like Orphenadrine is not typically advised due to potential side effects and tolerance. Chronic pain management requires a comprehensive plan from a healthcare professional, which may include other medications, physical therapy, and lifestyle modifications.
Does Wilgesic cause weight gain?
Weight gain is not a commonly reported side effect of Wilgesic. Some individuals might experience changes in appetite, but significant weight gain is unlikely. If you notice unusual changes, consult your doctor.
