Sofvasc-V Tab 5mg/80mg 14’s

Description

Sofvasc-V 5mg/80mg is a potent, prescription-only combination medication meticulously formulated for the effective management of hypertension, commonly known as high blood pressure. This advanced dual-therapy tablet integrates two first-line antihypertensive agents—Amlodipine, a calcium channel blocker, and Valsartan, an angiotensin II receptor blocker (ARB)—to provide a synergistic approach for relaxing blood vessels and reducing cardiovascular strain. It is designed for patients whose blood pressure remains uncontrolled on a single medication, offering a convenient, single-pill regimen that enhances treatment adherence and efficacy.

Below is a concise summary of the core product features and patient benefits you can expect from this integrated therapy:

✅ Dual-Mechanism Action: Utilizes two distinct pathways for vasodilation and blood pressure reduction.
✅ Enhanced Efficacy: Superior blood pressure-lowering effect compared to many monotherapies.
✅ Improved Adherence: One tablet regimen simplifies daily treatment, reducing the chance of missed doses.
✅ Cardiovascular Protection: Aims to reduce the long-term risk of heart attack and stroke.
✅ Trusted Formulation: Manufactured under stringent Good Manufacturing Practice (GMP) guidelines for assured quality and purity.

What Are the Primary Uses and Key Features of Sofvasc-V Tablets?

Sofvasc-V (Amlodipine and Valsartan) is clinically prescribed for specific cardiovascular conditions. Its key features are derived from the complementary actions of its active pharmaceutical ingredients.

Primary Therapeutic Uses and Indications

• Essential Hypertension Management: This is the primary use. It is indicated for adult patients with high blood pressure who require more than one drug to achieve their target blood pressure goals.

• Treatment of Hypertension Uncontrolled by Monotherapy: It is specifically beneficial for individuals whose blood pressure remains elevated despite treatment with either Amlodipine or Valsartan (or other drugs from their respective classes) alone.

• Blood Pressure Control in Various Patient Profiles: The combination can be effective across diverse patient groups, though a physician must determine suitability based on individual health status.

Distinguishing Key Features and Benefits

• Synergistic Pharmacological Action: Amlodipine prevents calcium from entering vascular smooth muscle and heart muscle, causing vasodilation. Valsartan blocks the angiotensin II receptor, inhibiting a key hormone that causes vasoconstriction and sodium retention. Together, they tackle high BP from multiple angles.

• Convenient Fixed-Dose Combination (FDC): Improves medication compliance by combining two essential drugs into one daily tablet, a significant advantage in chronic condition management.

• Potential for Reduced Side Effects: Using lower doses of each component in combination can sometimes minimize the dose-dependent adverse effects associated with high doses of a single drug.

• 24-Hour Sustained Activity: Both components are long-acting, providing smooth, round-the-clock blood pressure control with a single daily dose, protecting against morning blood pressure surges.

What Active Ingredients Are in Sofvasc-V and How Do They Work?

Sofvasc-V contains two well-established active ingredients in a fixed-dose combination. Understanding their individual roles clarifies the product’s overall efficacy.

Detailed Ingredient Breakdown

1. Amlodipine Besylate (5mg): This is a dihydropyridine calcium channel blocker (CCB). It works by selectively inhibiting the transmembrane influx of calcium ions into vascular smooth muscle cells and cardiac muscle cells. This inhibition leads to:

   • Peripheral Arterial Vasodilation: Relaxation of the blood vessel walls, decreasing peripheral vascular resistance.

   • Reduced Cardiac Afterload: The heart does not have to work as hard to pump blood, lowering blood pressure.

   • Minimal Impact on Heart Rate: Unlike some other CCBs, amlodipine has a very limited effect on heart rate and cardiac conduction.

2. Valsartan (80mg): This is a potent and specific angiotensin II receptor blocker (ARB). It selectively blocks the binding of angiotensin II to the AT1 receptor, which is found in many tissues. This action results in:

   • Vasodilation: Blocking angiotensin II prevents the constriction of blood vessels.

   • Aldosterone Inhibition: Reduces the secretion of aldosterone, leading to decreased sodium and water reabsorption by the kidneys.

   • Cardiac and Renal Protection: By blocking the renin-angiotensin-aldosterone system (RAAS), it provides protective effects on the heart and kidneys beyond just lowering blood pressure.

How Should I Take Sofvasc-V Tablets? Directions for Correct Use

Adhering to proper usage guidelines is critical for safety and achieving optimal therapeutic outcomes.

General Administration Guidelines

• Oral Consumption: Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.

• Timing and Consistency: Take your dose at the same time each day to maintain a steady level of medication in your bloodstream. This can be taken with or without food, but consistency is key.

• Never Double Dose: If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two tablets to make up for a missed dose.

• Continuous Treatment: Hypertension is a chronic condition. Continue taking Sofvasc-V even when you feel well, unless instructed otherwise by your doctor. Stopping suddenly can cause your blood pressure to rise sharply.

What is the Recommended Dosage Information for Sofvasc-V?

Dosage is individualized and must be determined by a healthcare professional. The following information is standard but not a substitute for medical advice.

Standard Adult Dosage for Hypertension

• Initial Therapy: The recommended starting dose for most patients new to this combination is one Sofvasc-V (5mg/80mg) tablet once daily.

• Dose Titration: Based on patient response and tolerability, a physician may adjust the dose. The maximum recommended daily dose is Amlodipine 10mg and Valsartan 320mg, which may be available in different strength combinations.

• Patients Already on Monotherapy: For patients already taking amlodipine or valsartan separately, the doctor will select the Sofvasc-V strength that provides an equivalent or appropriate dose of each component.

• Special Populations: Dosage adjustments may be necessary for elderly patients, those with liver impairment, or patients with severe renal impairment or on dialysis. A lower starting dose may be advised.

What Precautions and Warnings Are Associated with Sofvasc-V?

This medication has important safety considerations that must be heeded to prevent complications.

Critical Contraindications and Warnings

• Pregnancy Warning: This drug must NOT be used during pregnancy, especially in the second and third trimesters. It can cause injury and even death to the developing fetus. If you plan to become pregnant, inform your doctor immediately to switch to a safer alternative.

• Angioedema: Seek emergency medical attention if you experience swelling of the face, lips, tongue, throat, or difficulty swallowing or breathing, which could indicate angioedema.

• Hypotension (Low Blood Pressure): Excessive lowering of blood pressure may occur, especially in volume-depleted patients (e.g., on high-dose diuretics). Symptoms include dizziness, lightheadedness, and fainting.

• Renal Impairment: In patients with severe kidney disease or renal artery stenosis, treatment may cause renal function deterioration. Monitoring is essential.

• Hyperkalemia: Valsartan can increase serum potassium levels. Risk is higher in patients with diabetes, kidney problems, or those taking potassium supplements or potassium-sparing diuretics.

Important Precautions for Safe Use

• Medical History Disclosure: Inform your doctor if you have a history of heart disease (especially heart failure or aortic stenosis), liver disease, kidney disease, or electrolyte imbalances.

• Drug Interactions Disclosure: Provide your doctor and pharmacist with a complete list of all medications you take, including:

  • Other blood pressure or heart medications.

  • Diuretics (water pills).

  • Potassium supplements or salt substitutes containing potassium.

  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) like ibuprofen or naproxen.

  • Lithium.

• Surgery and Anesthesia: Inform the surgeon or anesthetist that you are taking this medication before any surgery.

What Are the Possible Side Effects of Sofvasc-V Tablets?

Like all medicines, Sofvasc-V can cause side effects, although not everybody gets them. They are often mild and temporary.

Commonly Reported Side Effects

• Peripheral Edema (Swelling): Swelling of the ankles and feet, more commonly associated with the amlodipine component.

• Dizziness or Lightheadedness: Especially when standing up quickly, due to a drop in blood pressure.

• Flushing: A feeling of warmth and redness in the face.

• Headache.

• Fatigue or Tiredness.

• Nasopharyngitis (Common Cold symptoms).

• Abdominal Pain or Nausea.

Serious Side Effects (Require Immediate Medical Attention)

While rare, discontinue use and contact your doctor immediately if you experience:

• Signs of Allergic Reaction: Rash, hives, severe itching.

• Symptoms of Angioedema: As described in the warnings.

• Rapid Heartbeat or Palpitations.

• Symptoms of Very High Potassium: Muscle weakness, slow or irregular heartbeat.

• Severe Dizziness or Fainting.

• Yellowing of Skin or Eyes (Jaundice): Could indicate liver problems.

• Signs of Kidney Problems: Significant change in urine amount, swelling in feet/ankles.

How Should I Store Sofvasc-V Tablets for Maximum Potency?

Proper storage ensures the stability, safety, and effectiveness of the medication throughout its shelf life.

Optimal Storage Conditions

• Temperature: Store below 30°C (86°F). Keep in a cool, dry place away from direct heat, sunlight, and moisture (do not store in bathrooms).

• Container: Keep the tablets in their original blister pack or bottle until use to protect from light and environmental factors.

• Safety: Keep out of reach and sight of children and pets to prevent accidental ingestion.

• Disposal: Do not use after the expiration date printed on the pack. Dispose of unused medicine properly through a pharmacy take-back program; do not flush down the toilet or throw in household trash.

Who Manufactures Sofvasc-V Tablets? Authoritative Manufacturer Information

Sofvasc-V Tablets are manufactured by Micro Labs Limited, a prominent and respected Indian multinational pharmaceutical company. The company is recognized for:

• Global GMP Compliance: Its manufacturing facilities adhere to World Health Organization (WHO-GMP) and other international Good Manufacturing Practice standards, ensuring product quality, purity, and consistency.

• Extensive Portfolio: Micro Labs has a strong focus on therapeutic areas including cardiology, diabetology, and central nervous system disorders.

• Commitment to Quality: The company employs rigorous quality control and assurance protocols at every stage of production, from sourcing active pharmaceutical ingredients (APIs) to final packaging.

• Research and Development: Continuous investment in R&D drives the development of effective and affordable medicines like Sofvasc-V.

What Are the Comprehensive Health Benefits of Using Sofvasc-V?

The benefits of this fixed-dose combination extend beyond simple blood pressure reduction, contributing to overall cardiovascular risk management.

Detailed List of Therapeutic Benefits

• Superior Blood Pressure Control: The dual-action mechanism often achieves greater reductions in both systolic (top number) and diastolic (bottom number) blood pressure than either component alone, helping more patients reach target BP goals.

• Reduced Cardiovascular Morbidity: Effective long-term hypertension control is proven to lower the risk of serious cardiovascular events, including:

  • Ischemic Heart Disease

  • Myocardial Infarction (Heart Attack)

  • Stroke (Cerebrovascular Accident)

  • Heart Failure

• Potential Organoprotective Effects: By blocking the RAAS system, valsartan may offer specific protective benefits for the kidneys (slowing diabetic nephropathy progression) and the heart (reducing remodeling after a heart attack).

• Enhanced Patient Compliance and Persistence: The single-tablet regimen significantly simplifies the treatment schedule. This is a major factor in improving long-term adherence, which is directly linked to better health outcomes in chronic hypertension management.

• Possible Favorable Side Effect Profile: The combination may allow for lower doses of each drug, potentially reducing the incidence or severity of side effects like ankle edema (from amlodipine) when used in combination with an ARB.

How Does Sofvasc-V Compare to Other Hypertension Treatments?

To understand where Sofvasc-V fits in the treatment landscape, here is a comparative analysis versus common alternatives.

Comparison Table: Sofvasc-V vs. Key Antihypertensive Alternatives

Frequently Asked Questions (FAQs) About Sofvasc-V Tablets

This section anticipates and answers real-world queries using natural, semantic language for voice search and LLMs.

Is Sofvasc-V a good medicine for high blood pressure?

Yes, Sofvasc-V is considered a highly effective and rational combination for treating hypertension. It combines two first-line drug classes, often providing better blood pressure control than single drugs and is recommended in major clinical guidelines for patients needing combination therapy.

Can I take Sofvasc-V tablet at night?

The optimal time should be decided by your doctor. Since it provides 24-hour control, taking it in the morning is common. However, some studies suggest nighttime dosing may better control morning surges. Consistency in timing is more important than the specific time of day.

Does Amlodipine and Valsartan combination cause weight gain?

Significant weight gain is not a typical side effect of this combination. Any minor weight fluctuation is usually related to fluid retention (edema), a known possible side effect of the amlodipine component. Report any sudden or significant weight gain to your physician.

What should I avoid while taking Amlodipine and Valsartan?

Avoid becoming pregnant. Limit alcohol as it can worsen dizziness. Be cautious with over-the-counter NSAIDs (like ibuprofen) and salt substitutes high in potassium unless approved by your doctor. Avoid activities requiring alertness until you know how the medicine affects you.

How long does it take for Sofvasc-V to lower blood pressure?

You may notice a reduction within 1-2 weeks, but the full therapeutic effect of this combination often takes 4-6 weeks of regular use. Do not stop taking it if you don’t feel an immediate effect; blood pressure management is a long-term process.

Can I stop taking Sofvasc-V if my BP is normal?

No. Your blood pressure is normal because the medication is working. Stopping suddenly can cause a dangerous rebound increase in blood pressure. Any change in dosage or discontinuation must be done under strict medical supervision.

Is coughing a side effect of Valsartan?

A persistent dry cough is a well-known side effect of ACE inhibitors (like lisinopril) but is rare with ARBs like Valsartan. This is a key reason doctors may choose an ARB over an ACE inhibitor for some patients.

Who should not take this Amlodipine Valsartan combination?

This medication is contraindicated for: pregnant women, individuals with a known hypersensitivity to any component, patients with severe liver impairment or biliary obstruction, and those with severe hypotension.