Ulcenil 120ml Syp

Description

Ulcenil 120ml Syrup is a trusted anti-acid medication formulated to provide effective relief from a spectrum of gastric disorders caused by excessive stomach acid production. This oral suspension contains Famotidine, a potent H2-receptor antagonist, offering a therapeutic solution for both acute symptom management and long-term treatment protocols. Manufactured under strict pharmacopeial standards, it is a reliable choice for patients seeking comfort from acid-related discomfort.

Here is a brief summary of what makes Ulcenil Syrup a recommended option:

• ✔️ Fast-Acting Acid Reduction: Targets histamine receptors to quickly decrease gastric acid secretion.

• ✔️ Multi-Condition Relief: Effectively manages GERD, peptic ulcers, heartburn, and hypersecretory conditions.

• ✔️ Convenient Liquid Form: Easy-to-swallow syrup ideal for adults who prefer liquids and for accurate pediatric dosing.

• ✔️ Trusted Manufacturing: Produced by Siza International in GMP-certified facilities, ensuring high purity and potency.

• ✔️ Preventative Benefits: Aids in healing and helps prevent the recurrence of duodenal and gastric ulcers.

What is Ulcenil Syrup and How Does It Work?

Ulcenil 120ml Syrup is an anti-ulcer pharmacotherapy belonging to the histamine H2-receptor blockers class. Its primary active pharmaceutical ingredient, Famotidine, functions as a competitive inhibitor of histamine at the parietal cell’s H2 receptors in the gastric lining. By blocking these receptors, it significantly inhibits both basal (fasting) and stimulus-induced gastric acid secretion. This action elevates gastric pH, creating a less acidic environment that allows inflamed esophageal tissue and ulcerated lesions in the stomach or duodenum to heal. Unlike simple antacids that neutralize existing acid, Ulcenil Syrup works at the physiological source to reduce acid production, providing longer-lasting relief and therapeutic correction.

What Are the Primary Uses and Key Features of Ulcenil Famotidine Syrup?

Ulcenil Syrup Uses and Indications
This gastrointestinal medication is clinically indicated for a variety of acid-peptic disorders. Healthcare providers prescribe it for:

• Gastroesophageal Reflux Disease (GERD) Management: Treats erosive esophagitis and provides symptomatic relief for the burning sensation of acid reflux disease.

• Peptic Ulcer Disease Treatment: Promotes the healing of active, benign gastric ulcers and duodenal ulcers.

• Ulcer Prophylaxis: Helps prevent the recurrence of duodenal ulcers after the acute phase has healed.

• Pathological Hypersecretion Conditions: Manages acid output in Zollinger-Ellison syndrome and systemic mastocytosis.

• Symptomatic Relief: Alleviates heartburn, acid indigestion, and sour stomach often associated with dietary habits.

Key Features and Benefits of This H2 Blocker Syrup

• Proven Efficacy: Famotidine has a well-documented history of efficacy in acid suppression and mucosal healing.

• Rapid Onset of Action: Begins reducing acid production quickly, offering relief from discomfort.

• Dosing Convenience: Typically administered once or twice daily, enhancing patient compliance compared to more frequent dosing regimens.

• Favorable Safety Profile: Generally well-tolerated by most patient demographics, including the elderly, under medical supervision.

• Sugar-Free Formulation: Often suitable for patients monitoring their sugar intake (check specific manufacturer formulation).

• Accurate Dosing: The syrup format allows for precise dose titration, which is crucial for pediatric use or for patients with specific dosage requirements.

What is the Active Ingredient in Ulcenil and How Does It Benefit You?

The sole active ingredient in Ulcenil 120ml Syrup is Famotidine. Each 5ml (one teaspoon) typically contains 10mg of Famotidine USP.

Famotidine Benefits and Pharmacological Action:
Famotidine is a second-generation H2 receptor antagonist. Its molecular structure allows it to bind selectively and potently to H2 receptors in the stomach. The key benefits stemming from this action include:

• Potent Acid Suppression: It is significantly more potent than earlier H2 blockers like cimetidine on a milligram-for-milligram basis, leading to effective and sustained elevation of intragastric pH.

• Dual-Phase Inhibition: Reduces both daytime and nighttime gastric acid secretion, making a bedtime dose particularly effective for nocturnal acid breakthrough.

• Promotes Healing Environment: By maintaining a higher gastric pH, it facilitates the natural healing process of ulcerated mucosa in the esophagus, stomach, and duodenum.

• Symptom Resolution: Directly addresses the root cause of symptoms like epigastric pain, regurgitation, and heartburn by reducing the volume and acidity of gastric fluid.

How Should You Use Ulcenil Syrup for Best Results?

Directions for Use and Administration
Correct administration is vital for optimal therapeutic outcomes and safety.

1. Shake Vigorously: Always shake the bottle well for 10-15 seconds before each use to ensure the suspension is uniform and the dose is accurate.

2. Measure Precisely: Use only the calibrated measuring cup or oral syringe provided with the product. Do not use household spoons, as they are not accurate.

3. Oral Consumption: Take the measured dose by mouth. It can be swallowed directly from the cup or syringe.

4. Timing with Food: It can be taken with or without food. However, for conditions like GERD, a dose taken 30-60 minutes before bedtime is often recommended to control nocturnal acid production.

5. Consistency: Take the medication at the same time(s) each day to maintain steady drug levels in your body.

6. Completion of Course: Even if symptoms improve, complete the full course prescribed by your doctor to ensure proper healing and prevent recurrence.

What is the Recommended Dosage of Ulcenil Famotidine Syrup?

Dosage Information for Various Conditions
Dosage is individualized based on the medical condition being treated, renal function, and patient response. The following are typical adult dosages. Pediatric dosing must be determined by a pediatrician based on body weight.

• For Active Duodenal Ulcer: 20 mg (10ml) twice daily or 40 mg (20ml) once at bedtime. Treatment course is typically 4-8 weeks.

• For Active Gastric Ulcer: 40 mg (20ml) once daily at bedtime for 6-8 weeks.

• For GERD and Erosive Esophagitis: 20 mg (10ml) twice daily for up to 12 weeks.

• For Heartburn and Acid Indigestion: 10-20 mg (5-10ml) as a single dose for symptom relief.

• For Ulcer Prevention (Maintenance Therapy): 20 mg (10ml) once daily at bedtime.

• For Zollinger-Ellison Syndrome: Starting dose is often 20 mg (10ml) every 6 hours, adjusted as needed. Doses may be significantly higher under medical supervision.

Important Note on Renal Dosing: Patients with moderate to severe kidney impairment (creatinine clearance <50 mL/min) require dosage adjustment, often a reduction in dose or an increase in dosing interval. Consultation with a doctor is mandatory.

What Precautions Should You Take Before Using This Acid Reflux Medicine?

Precautions and Contraindications
While Ulcenil is widely used, certain precautions ensure safe and effective treatment:

• Medical History Disclosure: Inform your doctor if you have a history of kidney disease, liver problems, porphyria, or stomach cancer.

• Drug Interactions: Famotidine may interact with certain drugs like ketoconazole, itraconazole (reducing their absorption), and atazanavir. Provide your doctor with a complete list of all medications, including over-the-counter drugs and herbal supplements.

• Pregnancy and Lactation: Use during pregnancy or breastfeeding only if clearly needed and under direct medical advice, as Famotidine is excreted in breast milk.

• Allergy Alert: Do not use if you have a known hypersensitivity to Famotidine or any other component of the syrup.

• Symptom Masking: Long-term acid suppression can mask symptoms of gastric malignancy. Any new or worsening symptoms like significant weight loss, persistent vomiting, or trouble swallowing warrant immediate medical evaluation.

• Not an Immediate Pain Reliever: This medication is not for immediate relief of heartburn; it may take 1-2 hours to start working. Do not use it for occasional heartburn without a doctor’s diagnosis for ongoing conditions.

Are There Any Potential Side Effects of Ulcenil 120ml Syrup?

Possible Adverse Reactions and Side Effects
Most patients tolerate Famotidine syrup well. Side effects, when they occur, are usually mild and transient. They can be categorized as:

Common Side Effects (Generally Mild):

• Central Nervous System: Headache, dizziness, drowsiness.

• Gastrointestinal: Constipation, diarrhea, nausea, vomiting, abdominal discomfort.

• General: Fatigue.

Less Common or Rare Side Effects (Require Medical Attention):

• Allergic Reactions: Rash, itching, hives, swelling of the face/lips/tongue, difficulty breathing.

• Blood Disorders: Rare reports of reversible leukopenia, thrombocytopenia.

• Hepatic Effects: Reversible elevated liver enzymes, jaundice.

• Cardiovascular: Palpitations, bradycardia (slow heart rate).

• Neurological: Confusion, especially in ill or elderly patients, hallucinations.

• Musculoskeletal: Muscle or joint pain.

If you experience any severe or persistent side effects, discontinue use and consult your healthcare provider promptly.

How Should You Store This Gastric Medicine Properly?

Storage Instructions for Stability and Safety
Proper storage maintains the drug’s efficacy and shelf life.

• Temperature: Store at room temperature, between 15°C to 30°C (59°F to 86°F). Do not freeze.

• Container: Keep tightly capped in the original bottle to protect from light and moisture.

• Location: Store in a cool, dry place away from direct sunlight and heat sources. Keep out of reach of children and pets.

• Post-Mixing: If the pharmacist has reconstituted the powder to form the syrup, note the expiry date on the label, which is typically shorter than the shelf-life of the unopened powder.

• Disposal: Do not use after the expiration date printed on the packaging. Dispose of unused medicine safely, preferably through a pharmacy take-back program.

Who Manufactures Ulcenil Syrup and What Are Their Credentials?

Manufacturer Information and Quality Assurance
Ulcenil 120ml Syrup is manufactured by Siza International (Pvt) Ltd., a pharmaceutical company based in Pakistan. Reputable manufacturers like Siza International adhere to stringent quality control protocols to ensure product safety and consistency.

• GMP Compliance: The product is manufactured in facilities that follow Good Manufacturing Practices (GMP), an international standard that ensures products are consistently produced and controlled according to quality standards.

• Quality Sourcing: The active pharmaceutical ingredient (Famotidine) is sourced from reliable suppliers and undergoes rigorous testing for purity, potency, and identity.

• Regulatory Oversight: The manufacturing process and final product are subject to oversight by national drug regulatory authorities, which helps ensure compliance with safety and efficacy standards.

• Trust and Traceability: Choosing a product from a known manufacturer provides traceability and accountability, which is crucial for pharmaceutical products.

What Are the Comprehensive Health Benefits of Using Ulcenil?

Detailed List of Therapeutic Benefits
Using Ulcenil Syrup as prescribed offers a multi-faceted approach to gastrointestinal health:

• Effective GERD Symptom Control: Reduces the frequency and severity of heartburn and regurgitation, improving quality of life and sleep.

• Promotes Mucosal Healing: Creates an optimal pH environment for the natural healing of erosions and ulcers in the esophagus, stomach, and duodenum, preventing complications like bleeding or perforation.

• Prevents Ulcer Recurrence: Maintenance therapy significantly lowers the chance of ulcer return, especially in high-risk patients.

• Manages Hypersecretory States: Provides a non-invasive means to control debilitating conditions like Zollinger-Ellison syndrome.

• Reduces Acid-Related Discomfort: Offers relief from non-ulcer dyspepsia, sour stomach, and acid indigestion.

• May Improve Respiratory Symptoms: In some patients with asthma or chronic cough exacerbated by acid reflux, controlling GERD can improve respiratory outcomes.

• Supports Concurrent Therapy: Used in conjunction with antibiotics for H. pylori eradication regimens to enhance effectiveness.

• Convenient Administration: The liquid form is beneficial for patients with swallowing difficulties (dysphagia) and allows for easy dose adjustment.

How Does Ulcenil (Famotidine) Compare to Other Acid Reducers?

Comparison Table: Ulcenil (Famotidine) vs. Key Alternatives

Frequently Asked Questions About Ulcenil Famotidine Syrup

How long does it take for Ulcenil Syrup to work for heartburn?
You may start to feel relief from heartburn within 1 to 2 hours after taking a dose of Ulcenil Syrup, as Famotidine begins to reduce acid production. For complete healing of esophagitis or ulcers, it may take several weeks of consistent use as prescribed.

Can I take Ulcenil Syrup for a long period?
Ulcenil can be used for long-term maintenance therapy to prevent ulcer recurrence or manage chronic conditions like Zollinger-Ellison syndrome under strict medical supervision. For uncomplicated GERD, doctors often recommend the shortest effective duration. Regular check-ups are advised for long-term users.

Is Ulcenil safe for children?
Famotidine can be used in pediatric patients, but the dose is carefully calculated based on the child’s body weight (mg/kg). You must never self-medicate a child with Ulcenil Syrup. Always consult a pediatrician for an accurate diagnosis, appropriate dosage, and duration of treatment.

What should I do if I miss a dose of my stomach acid medicine?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one, as this increases the risk of side effects.

Can I consume alcohol while taking this anti-ulcer medication?
It is generally advised to limit or avoid alcohol while being treated for acid-related disorders. Alcohol can increase stomach acid production and irritate the stomach lining, potentially counteracting the benefits of Ulcenil and delaying healing. Discuss this with your doctor.

Does Famotidine cause weight gain?
Weight gain is not a commonly reported side effect of Famotidine. If you experience significant or unexplained weight changes while on medication, it is important to consult your doctor to rule out other causes or conditions.

Can I take Ulcenil with antibiotics for an H. pylori infection?
Yes, Famotidine is sometimes used as part of combination therapy to treat Helicobacter pylori infections, which are a common cause of peptic ulcers. It is often used alongside antibiotics and other medications like bismuth subsalicylate. Your doctor will prescribe the specific regimen.