NISE TABLET 100MG 2X10S

Description

Nise Tablet 100mg is a trusted non-steroidal anti-inflammatory drug (NSAID) specifically formulated to provide effective relief from various types of pain and inflammation. Its active ingredient, Nimesulide, works by targeting the root cause of discomfort, making it a go-to solution for conditions like arthritis, muscle aches, and post-operative pain. This medication is designed for those seeking rapid and powerful analgesic and anti-inflammatory action.

Here is a brief summary of what makes Nise Tablet 100mg a preferred choice:

• ✓ Potent Pain Relief: Quickly alleviates moderate to severe pain.

• ✓ Strong Anti-inflammatory Action: Reduces swelling and inflammation at the source.

• ✓ Trusted NSAID Formula: Contains Nimesulide, a well-researched active ingredient.

• ✓ Convenient Dosage: The 100mg strength is suitable for adult pain management.

What are the Primary Uses and Key Features of Nise Tablet 100mg?

Nise Tablet 100mg is a versatile medication prescribed for a range of painful and inflammatory conditions. Its primary mechanism involves inhibiting cyclooxygenase-2 (COX-2) enzymes, which are responsible for pain and inflammation signals in the body.

Primary Therapeutic Uses of Nise 100mg

This medication is commonly recommended for managing:

• Osteoarthritis Pain: Provides significant relief from joint pain and stiffness associated with degenerative joint disease.

• Rheumatoid Arthritis: Helps reduce inflammation and pain in joints affected by this autoimmune condition.

• Acute Musculoskeletal Pain: Effective for treating back pain, sprains, and strains.

• Postoperative Analgesia: Manages pain following surgical procedures and dental treatments.

• Dysmenorrhea: Offers relief from intense pain and cramping during menstrual periods.

• ENT (Ear, Nose, Throat) Disorders: Used in the management of pain and inflammation associated with conditions like tonsillitis and pharyngitis.

Key Features and Benefits of Choosing Nise

• Dual Action: Functions as both an analgesic (pain reliever) and an anti-inflammatory agent.

• Rapid Onset of Action: It is known for its quick absorption, leading to faster pain relief compared to some other NSAIDs.

• Convenient Dosage Regimen: The typical twice-daily dosage makes it easy to incorporate into a daily routine.

• GMP Certified Manufacturing: Ensures the product meets high standards of quality, safety, and efficacy.

What is the Key Ingredient in Nise Tablet 100mg?

The therapeutic power of Nise Tablet 100mg comes from its single, potent active ingredient.

Active Pharmaceutical Ingredient (API)

• Nimesulide (100mg): This is the primary and only active component responsible for the drug’s effects. Nimesulide belongs to the sulfonanilide class of NSAIDs and is a selective COX-2 inhibitor.

How Does Nimesulide Work in the Body?

Nimesulide provides relief by specifically targeting and blocking the cyclooxygenase-2 (COX-2) enzyme. This enzyme plays a key role in producing prostaglandins, which are chemicals that promote inflammation, pain, and fever. By reducing prostaglandin levels at the inflamed site, Nimesulide effectively diminishes pain and swelling with a favorable gastrointestinal tolerance profile for many users. The inactive ingredients, or excipients, in the tablet ensure stability, proper dissolution, and shelf life.

How Should I Use Nise Tablet 100mg Correctly?

For optimal results and safety, it is crucial to follow the correct method of administration.

Directions for Use

• Administration: Take the Nise tablet orally with a full glass of water.

• Timing: It is best consumed after a meal to minimize the potential for stomach upset or gastric irritation.

• Do Not Crush or Chew: Swallow the tablet whole; do not break, crush, or chew it.

• Consistency: Adhere to a fixed schedule for your doses to maintain a consistent level of the medicine in your bloodstream.

What is the Recommended Dosage for Nise Tablet 100mg?

Dosage must always be determined by a healthcare professional based on your specific medical condition and response to treatment.

Standard Adult Dosage Information

• Typical Dose: The usual recommended adult dose is one Nise 100mg tablet twice daily.

• Maximum Daily Limit: It is generally advised not to exceed 200mg (two tablets) in a 24-hour period.

• Duration of Treatment: The treatment course should be as short as possible. Typically, a treatment duration of 15 days is considered the maximum for most acute conditions. Long-term use should only be under strict medical supervision.

• Special Populations: Dosage adjustments are necessary for elderly patients and those with impaired kidney or liver function. A doctor will prescribe a lower dose or different medication if needed.

What Precautions Should I Take with Nise 100mg?

While Nise is effective, certain precautions are essential for safe use.

Important Warnings and Contraindications

• Allergy Alert: Do not use this medicine if you are allergic to Nimesulide, other NSAIDs (like aspirin, ibuprofen), or any of the tablet’s inactive ingredients.

• Pregnancy and Breastfeeding: Contraindicated during the third trimester of pregnancy and not recommended for use during the first and second trimesters or while breastfeeding without consulting a doctor.

• Pre-existing Conditions: Use with extreme caution if you have a history of:

  • Peptic ulcer or stomach bleeding

  • Severe heart, kidney, or liver disease

  • High blood pressure

  • Bleeding disorders

• Alcohol Consumption: Avoid alcohol consumption while taking Nise, as it increases the risk of stomach bleeding and liver damage.

• Drug Interactions: Inform your doctor about all other medications you are taking, especially blood thinners (e.g., warfarin), other NSAIDs, diuretics, and certain antidepressants (SSRIs).

What are the Possible Side Effects of Nise Tablet 100mg?

Like all medicines, Nise can cause side effects, although not everybody gets them.

Common and Less Serious Side Effects

These are usually mild and may subside as your body adjusts to the medicine:

• Nausea, indigestion, or stomach discomfort

• Diarrhea or constipation

• Dizziness or drowsiness

• Skin rash or itching

Serious Side Effects Requiring Immediate Medical Attention

Stop taking Nise and seek immediate medical help if you experience any of these rare but severe side effects:

• Signs of stomach bleeding: Vomiting blood or what looks like coffee grounds, black or tarry stools.

• Symptoms of liver problems: Yellowing of the skin or eyes (jaundice), dark urine, severe stomach pain, persistent nausea.

• Signs of an allergic reaction: Swelling of the face, lips, tongue, or throat, difficulty breathing, severe skin rashes.

• Signs of heart problems: Chest pain, shortness of breath, weakness on one part of your body, slurred speech.

How Should I Store Nise Tablet 100mg?

Proper storage is vital to maintain the drug’s potency and safety.

Storage Instructions

• Temperature: Store below 30°C (86°F) in a cool, dry place.

• Moisture: Keep the tablets in their original blister strip to protect them from moisture and light.

• Accessibility: Always keep the medicine out of the sight and reach of children and pets.

• Expiry: Do not use the medicine after the expiration date printed on the packaging.

Who is the Manufacturer of Nise Tablet?

Manufacturer Information

Nise Tablet is manufactured by Panacea Biotec Ltd., a leading and well-respected Indian pharmaceutical company known for its commitment to research, development, and manufacturing of high-quality medicines. The company operates state-of-the-art facilities that are compliant with WHO-GMP (World Health Organization – Good Manufacturing Practices) standards, ensuring that every tablet meets stringent international quality and safety benchmarks.

What are the Main Health Benefits of Using Nise Tablet 100mg?

The benefits of Nise Tablet 100mg extend beyond simple pain relief, offering a comprehensive approach to managing inflammatory pain conditions.

Comprehensive Health Benefits

• Effective Pain Management: Provides powerful relief from various types of acute and chronic pain, improving mobility and quality of life.

• Reduction of Inflammation: Directly targets and reduces inflammatory mediators, addressing the underlying cause of swelling and pain in conditions like arthritis.

• Improved Joint Function: By alleviating pain and inflammation in joints, it helps restore range of motion and facilitates daily activities.

• Faster Recovery from Injury: Helps manage pain and swelling from sprains and strains, aiding the body’s natural healing process.

• Enhanced Comfort During Menstruation: Significantly reduces the severity of menstrual cramps, allowing for normal daily functioning.

How Does Nise 100mg Compare to Other Pain Relievers?

Understanding how Nise stands against common alternatives can help users and healthcare professionals make informed choices.

Nise Tablet (Nimesulide) vs. Common NSAIDs

Frequently Asked Questions (FAQs) About Nise Tablet 100mg

Can I take Nise 100mg for a headache?
Yes, Nise 100mg can be effective for relieving headaches, particularly tension headaches and migraines, due to its potent analgesic properties. However, it is always best to consult a doctor for persistent or severe headaches.

Is Nise tablet safe for long-term use in knee pain?
For chronic conditions like osteoarthritis knee pain, long-term use of any NSAID, including Nise, requires strict medical supervision. Doctors typically prescribe the lowest effective dose for the shortest possible duration due to potential risks to the kidneys, liver, and cardiovascular system. It is not typically recommended as a first-line long-term therapy.

What should I do if I miss a dose of Nise?
If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

Can I take Nise and Paracetamol together for better pain relief?
Combining Nise and Paracetamol can sometimes be recommended by a doctor for enhanced analgesic effect, as they work through different mechanisms. However, you should never self-medicate with this combination without a doctor’s prescription, as it requires professional assessment of your specific condition and risks.

How long does it take for a Nise tablet to start working?
Nimesulide is known for its relatively rapid absorption. Most users begin to feel pain relief within 15 to 30 minutes after ingestion, with the effect peaking around 1 to 3 hours.

Is Nise an antibiotic or a painkiller?
Nise is a painkiller, specifically a non-steroidal anti-inflammatory drug (NSAID). It is not an antibiotic and has no effect on bacterial or viral infections.