MOXIGET TABLET 400 MG 5S

Description

MOXIGET TABLET 400 MG is a powerful prescription antibiotic medication containing Moxifloxacin, designed to combat a spectrum of serious bacterial infections. This advanced fluoroquinolone agent works by systematically inhibiting bacterial growth, effectively treating conditions affecting the sinuses, lungs, and skin. It is a trusted solution for healthcare providers when targeting susceptible bacteria.

Here is a brief overview of what makes MOXIGET TABLET 400 MG a reliable choice for bacterial infection treatment:

• ✓ Targets a broad range of susceptible bacteria

• ✓ Effective for respiratory tract and skin infections

• ✓ Convenient once-daily dosing regimen

• ✓ Manufactured under strict Good Manufacturing Practices (GMP)

• ✓ Prescription-only, ensuring professional medical oversight

What is MOXIGET TABLET 400 MG and What Are Its Primary Uses?

MOXIGET is an advanced-generation fluoroquinolone antibiotic. Its active ingredient, Moxifloxacin, is a broad-spectrum antimicrobial agent prescribed by doctors to eradicate susceptible bacterial strains causing infections in various parts of the body.

Understanding the Mechanism of Action: How Does Moxifloxacin Work?
Moxifloxacin, the core component of MOXIGET, functions by selectively targeting two critical bacterial enzymes: DNA gyrase and topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, repair, and recombination. By inhibiting these enzymes, Moxifloxacin causes irreversible damage to the bacterial DNA, leading to the rapid death of the infectious microorganisms. This bactericidal action helps in effectively clearing the infection.

What Conditions Does MOXIGET TABLET 400 MG Treat?

MOXIGET tablets are specifically indicated for the treatment of adults with the following bacterial infections, caused by susceptible strains of microorganisms:

Respiratory Tract Infections

• Acute Bacterial Sinusitis: Effectively targets bacteria like Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis, relieving sinus pressure, pain, and congestion.

• Acute Bacterial Exacerbation of Chronic Bronchitis: Manages flare-ups in patients with chronic bronchitis, reducing symptoms like increased sputum production and shortness of breath, commonly caused by S. pneumoniae, H. influenzae, and others.

• Community-Acquired Pneumonia: Used to treat lung infections acquired outside of hospital settings, including those caused by a wider range of bacteria, offering a robust therapeutic option.

Skin and Soft Tissue Infections

• Complicated Skin and Skin Structure Infections (cSSSI): Treats deeper skin wounds, abscesses, and infected ulcers that involve deeper soft tissues, often addressing polymicrobial infections.

What is the Active Ingredient in MOXIGET TABLET 400 MG?

The sole active pharmaceutical ingredient in MOXIGET tablets is Moxifloxacin Hydrochloride, equivalent to 400 mg of Moxifloxacin.

Key Ingredient Benefits and Profile
Moxifloxacin is a synthetic, broad-spectrum antibacterial agent from the fluoroquinolone class. Its key benefits stem from its pharmacokinetic and pharmacodynamic properties:

• High Bioavailability: It is well-absorbed from the gastrointestinal tract, ensuring that a high percentage of the drug enters your system.

• Broad-Spectrum Activity: It is effective against a wide array of Gram-positive and Gram-negative bacteria, as well as atypical pathogens.

• Excellent Tissue Penetration: It effectively reaches the site of infection, such as sinus cavities, lung tissue, and skin structures, at concentrations required to kill bacteria.

How Should I Take MOXIGET TABLET 400 MG?

Correct usage is vital for the effectiveness of the treatment and to minimize the risk of side effects.

Step-by-Step Administration Guide

1. Follow Medical Prescription: Take MOXIGET exactly as prescribed by your doctor. Do not alter the dose or duration.

2. Timing and Frequency: The typical dose is one 400 mg tablet once every 24 hours.

3. With or Without Food: You can take MOXIGET with or without meals. Swallow the tablet whole with a full glass of water.

4. Consistency: Try to take it at the same time each day to maintain a consistent level of the drug in your body.

5. Complete the Course: It is crucial to finish the entire course of antibiotics, even if you start to feel better, to prevent the infection from returning and to avoid antibiotic resistance.

What is the Recommended Dosage of MOXIGET TABLET 400 MG?

The standard dosage for all approved indications in adults is one 400 mg tablet taken orally once daily.

Duration of Treatment for Different Infections
The treatment duration is determined by your healthcare provider based on the type and severity of the bacterial infection.

Always adhere to the specific duration prescribed by your doctor.

What Precautions Should I Take Before Using MOXIGET?

Moxifloxacin is a potent drug, and certain precautions are necessary for safe use.

Critical Warnings and Contraindications

• Tendonitis and Tendon Rupture: Moxifloxacin can increase the risk of tendon inflammation and rupture, particularly the Achilles tendon, in patients of all ages. This risk is higher in those over 60, and in those taking corticosteroid medications or with a history of organ transplants.

• Peripheral Neuropathy: Serious nerve damage causing pain, burning, tingling, or weakness can occur and may be irreversible. Discontinue use immediately if you experience these symptoms.

• Central Nervous System Effects: The drug may cause dizziness, lightheadedness, or seizures. Use caution when driving or operating machinery.

• Exacerbation of Myasthenia Gravis: It can worsen muscle weakness in individuals with myasthenia gravis and should be avoided.

• Hypersensitivity Reactions: Serious allergic reactions can occur. Inform your doctor immediately of any rash, itching, or swelling.

• QT Prolongation: Moxifloxacin can prolong the QT interval on an ECG, increasing the risk of serious irregular heart rhythms. It is contraindicated in individuals with known QT prolongation or those taking other drugs that prolong the QT interval.

Who Should Avoid MOXIGET TABLET 400 MG?

• Patients with a history of hypersensitivity to Moxifloxacin or any other quinolone antibiotic.

• Pregnant women and breastfeeding mothers, unless explicitly advised by a doctor.

• Children and adolescents under 18 years of age due to risks of musculoskeletal disorders.

• Patients with known QT prolongation or uncorrected electrolyte imbalances.

What Are the Potential Side Effects of MOXIGET TABLET 400 MG?

Like all medicines, MOXIGET TABLET 400 MG can cause side effects, although not everybody gets them.

Common Side Effects
These are usually mild to moderate and may disappear as your body adjusts to the medicine.

• Nausea and diarrhea

• Dizziness or lightheadedness

• Headache

• Abdominal pain

Serious Side Effects (Contact Your Doctor Immediately)

• Signs of tendon injury (pain, swelling, inflammation).

• Symptoms of peripheral neuropathy (pain, burning, tingling, weakness).

• Signs of a severe allergic reaction (skin rash, itching, difficulty swallowing or breathing).

• Persistent, severe diarrhea (which could indicate a bowel condition called C. difficile-associated diarrhea).

• Palpitations, fainting, or irregular heartbeat.

• Jaundice (yellowing of skin or eyes) or dark urine, indicating liver problems.

• Signs of a central nervous system reaction (tremors, restlessness, anxiety, confusion, hallucinations, depression).

How Should I Store MOXIGET Tablets?

Proper storage ensures the stability and efficacy of the medication.

• Store in a cool, dry place, away from direct sunlight and moisture.

• Keep the tablets in their original blister pack until use to protect them.

• The ideal storage temperature is below 30°C.

• Keep the medicine out of the reach of children and pets.

• Do not use the tablets after the expiration date printed on the packaging.

Who Manufactures MOXIGET Tablets?

MOXIGET tablets are manufactured by Glenmark Pharmaceuticals, a globally recognized, research-led pharmaceutical company. Glenmark is committed to delivering high-quality, affordable medicines and maintains manufacturing facilities that comply with the World Health Organization (WHO) Good Manufacturing Practices (GMP) and other stringent international regulatory standards. This ensures that every tablet meets rigorous criteria for purity, potency, and safety.

What Are the Key Benefits of Choosing MOXIGET?

Choosing MOXIGET for your bacterial infection treatment offers several distinct advantages:

• Broad-Spectrum Efficacy: Its wide coverage makes it effective against many common and atypical pathogens.

• Convenient Dosing: The once-daily regimen enhances patient compliance, which is critical for successful treatment outcomes.

• Proven Clinical Success: Moxifloxacin has a long history of use and is recommended in various clinical guidelines for the treatment of respiratory infections.

• High Quality Assurance: Being manufactured by Glenmark under GMP standards provides a trust signal regarding its quality and reliability.

• Rapid Action: As a bactericidal agent, it begins to kill susceptible bacteria quickly, leading to a faster onset of symptom relief.

How Does MOXIGET Compare to Other Antibiotics?

This table provides a general comparison. Your doctor is the best person to decide the most appropriate antibiotic for your specific condition.

Frequently Asked Questions About MOXIGET

Can I drink alcohol while taking MOXIGET?
It is generally advised to avoid alcohol while on any antibiotic treatment. Although alcohol does not directly reduce the efficacy of Moxifloxacin, it can worsen certain side effects like dizziness, lightheadedness, and stomach upset, and may place additional stress on your liver while your body is fighting an infection.

What should I do if I miss a dose of MOXIGET?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How long does it take for MOXIGET to start working?
You may start to feel symptom improvement within 2 to 3 days of starting the treatment as the drug begins to kill the bacteria. However, it is essential to complete the full prescribed course to ensure the infection is completely eradicated and to prevent recurrence or antibiotic resistance.

Can MOXIGET be used for a urinary tract infection (UTI)?
No, MOXIGET is not typically prescribed for urinary tract infections. Moxifloxacin is excreted in various body fluids but is not primarily concentrated in the urine. Other antibiotics like Ciprofloxacin (another fluoroquinolone) or Nitrofurantoin are more commonly used for UTIs.

Are there any specific foods I should avoid with Moxifloxacin?
You should avoid taking Moxifloxacin with dairy products, calcium-fortified juices, or antacids containing calcium, magnesium, or aluminum. These can significantly interfere with the absorption of the drug from your stomach. Take MOXIGET at least 2 hours before or 4 hours after consuming these products.

Is a prescription required to purchase MOXIGET tablets?
Yes, absolutely. MOXIGET 400mg is a prescription-only medication. It must be prescribed by a qualified healthcare professional after a proper diagnosis to ensure it is the correct and safe treatment for your specific bacterial infection.