Furolin Tablets 100mg (30 Tablets)

Description

Furolin Tablets 100mg offer a targeted and effective approach to managing and preventing uncomplicated urinary tract infections (UTIs). Each pack contains a full course of 30 tablets, formulated with the established antibacterial agent Nitrofurantoin. This medication works specifically within the urinary tract to eliminate the bacteria responsible for infection, providing relief from discomfort and supporting overall urinary system health. Manufactured under strict pharmacological standards, Furolin is a frontline defense for recurrent cystitis and other lower urinary tract infections.

Here is a brief summary of what makes Furolin Tablets a reliable choice:
✔️ Contains 100mg of Nitrofurantoin per tablet, a proven antibiotic for UTIs.
✔️ Specifically targets urinary tract pathogens with minimal systemic absorption.
✔️ Convenient 30-tablet pack for completing prescribed treatment courses.
✔️ Manufactured in GMP-certified facilities ensuring purity and potency.
✔️ Used for both treatment of active UTIs and long-term prevention of recurrence.

What is Furolin Tablets 100mg and What is it Used For?

Furolin is the brand name for a medication whose active ingredient is Nitrofurantoin. It belongs to a class of drugs known as nitrofuran antibiotics. Its primary and most effective use is within the domain of urinary tract health.

Primary Therapeutic Uses of Furolin Tablets 100mg
The core function of Furolin 100mg is the management of bacterial infections localized in the urinary system.

• Treatment of Acute Uncomplicated Cystitis: This is the most common use. It effectively treats lower urinary tract infections (bladder infections) caused by susceptible strains of bacteria like Escherichia coli (E. coli), Staphylococcus saprophyticus, and some strains of Klebsiella and Enterobacter.

• Management of Asymptomatic Bacteriuria: In certain patient profiles (e.g., before some urological procedures), Furolin may be used to eliminate bacteria present in the urine that are not currently causing symptoms but pose a risk.

• Prophylaxis (Prevention) of Recurrent UTIs: For individuals who experience frequent UTIs, a low-dose, long-term regimen of Furolin is often prescribed to prevent new infections from occurring.

Key Features and Benefits of Choosing Furolin

• Urinary Tract-Specific Action: Nitrofurantoin is uniquely concentrated in the urine, meaning it delivers its antibacterial effect precisely where it’s needed, which can be an advantage over broader-spectrum antibiotics.

• Proven Efficacy Against Common UTI Pathogens: It remains highly effective against the most frequent cause of UTIs, E. coli, including some strains resistant to other common antibiotics like sulfonamides.

• Minimal Impact on Gut Flora: Because it is poorly absorbed systemically and acts locally in the urinary tract, it is less likely to cause the significant intestinal dysbiosis (disruption of gut bacteria) associated with many other oral antibiotics.

• Convenient Dosage Form: The 100mg strength tablet allows for flexible dosing regimens as directed by a physician, and the 30-tablet pack is designed for complete treatment cycles.

What is the Active Ingredient in Furolin?

The sole active pharmaceutical ingredient in Furolin Tablets is Nitrofurantoin 100mg. It is a synthetic antibacterial agent derived from the nitrofuran class.

How Does Nitrofurantoin Work?
Nitrofurantoin’s mechanism of action is distinct. It is taken up by bacterial cells in the urinary tract and interferes with several bacterial enzyme systems, including acetylcoenzyme A, which is crucial for carbohydrate metabolism. More critically, it causes damage to bacterial DNA. This multi-target attack makes it bactericidal (kills bacteria) at therapeutic concentrations in urine. Its effectiveness is selective because it requires activation by bacterial enzymes, which are not present in human cells, contributing to its targeted action.

How Should I Take Furolin Tablets for Best Results?

General Directions for Use
Always follow the exact dosage instructions provided by your doctor or pharmacist. The following are general guidelines.

1. Administration: Take Furolin tablets orally by mouth.

2. With Food or Milk: To enhance absorption and significantly reduce the potential for stomach upset or nausea, take Furolin with food or milk. This is a crucial step for tolerability.

3. Swallow Whole: Swallow the tablet whole with a full glass of water. Do not crush, split, or chew the tablet.

4. Hydration: Maintain adequate fluid intake while on this medication to help flush the urinary tract, unless otherwise advised by your doctor due to a specific condition.

What is the Correct Dosage of Furolin 100mg?

Dosage is strictly individualized based on the indication (treatment vs. prevention), renal function, and patient age. The following table outlines common regimens.

Furolin (Nitrofurantoin) Dosage Guidelines

Important: This is for informational purposes. Your prescribing physician will determine the exact dosage and duration suitable for your specific medical condition.

What Precautions Should I Be Aware of Before Taking Furolin?

Critical Warnings and Contraindications

• Renal (Kidney) Impairment: Do not use if you have severe kidney disease or a creatinine clearance below 60 mL/min. The drug does not reach effective concentrations in the urine and systemic toxicity risk rises.

• Pregnancy Term Warning: Contraindicated at term (38-42 weeks gestation) and during labor and delivery due to risk of hemolytic anemia in the newborn.

• History of Allergic Reaction: Do not take if you have a known hypersensitivity to Nitrofurantoin or any other nitrofuran antibiotic.

• G6PD Deficiency: Patients with glucose-6-phosphate dehydrogenase deficiency are at risk for hemolytic anemia (destruction of red blood cells). Use with extreme caution.

• Hepatotoxicity: Rare but severe liver reactions have been reported. Discontinue immediately if signs of liver injury occur (e.g., yellowing skin/eyes, dark urine, severe abdominal pain).

Other Important Precautions

• Peripheral Neuropathy: Potentially irreversible nerve damage has occurred, risk is higher with prolonged use, renal impairment, anemia, diabetes, electrolyte imbalance, or vitamin B deficiency.

• Pulmonary Reactions: Acute and chronic lung reactions (like pneumonitis or fibrosis) can occur. Report any new or worsening cough, breathlessness, or chest pain.

• Superinfection: Use may result in overgrowth of non-susceptible organisms, including fungi. Report any new symptoms.

• Drug Interactions: Inform your doctor if you take antacids containing magnesium trisilicate, probenecid, or sulfinpyrazone, as they may affect Furolin’s efficacy.

• Breastfeeding: Nitrofurantoin is excreted in breast milk and may cause hemolytic anemia in G6PD-deficient infants. Consult your doctor.

What are the Possible Side Effects of Nitrofurantoin?

Like all medicines, Furolin can cause side effects, although not everybody gets them.

Common Side Effects (Generally Mild)
se may affect up to 1 in 10 people and often diminish when taken with food.

• Gastrointestinal disturbances: Nausea, loss of appetite, abdominal pain, diarrhea.

• Headache, dizziness.

• Changes in urine color (to dark yellow or brown) – this is harmless.

Uncommon to Rare but Serious Side Effects
Stop taking Furolin and seek immediate medical attention if you experience symptoms of:

• Allergic Reactions: Skin rash, itching, hives, swelling of face/lips/tongue, difficulty breathing.

• Pulmonary Toxicity: Fever, chills, cough, chest pain, shortness of breath.

• Hepatotoxicity: Yellowing of skin/eyes (jaundice), dark urine, severe stomach pain, persistent nausea.

• Peripheral Neuropathy: Numbness, tingling, or burning sensations in hands or feet.

• Hemolytic Anemia: Unusual tiredness, rapid heart rate, yellow skin, dark urine (especially in those with G6PD deficiency).

How Should I Store Furolin Tablets?

Proper storage ensures the stability and safety of your medication.

• Store below 25°C (77°F) in a dry place.

• Protect from light. Keep the tablets in their original blister pack inside the carton until use.

• Keep out of sight and reach of children.

• Do not use after the expiry date printed on the pack.

• Do not flush medicines down the toilet or pour them down a drain. Consult your pharmacist on safe disposal.

Who Manufactures Furolin Tablets?

Manufacturer and Quality Assurance
Furolin Tablets are manufactured by PharmEvo (Pvt.) Ltd., a leading and reputable pharmaceutical company based in Pakistan. PharmEvo operates state-of-the-art manufacturing facilities that are compliant with Good Manufacturing Practices (GMP) as set by international regulatory bodies. This ensures that every batch of Furolin 100mg tablets meets stringent standards of identity, strength, quality, and purity. The company’s commitment to research, development, and quality control provides a strong foundation of trust and authority for this product.

What are the Key Benefits of Using Furolin for UTIs?

Targeted Therapeutic Benefits

• Rapid Relief from UTI Symptoms: Effectively reduces the burning sensation during urination, urgency, frequency, and pelvic discomfort associated with cystitis.

• High Bacterial Eradication Rate: Achieves high urine concentration to effectively clear susceptible bacterial infections from the bladder and urinary tract.

• Prevention of Complicated Infections: By promptly treating lower UTIs, it helps prevent the ascent of infection to the kidneys (pyelonephritis), which is a more serious condition.

• Prophylaxis for Recurrent Infections: The long-term, low-dose regimen can break the cycle of frequent UTIs, greatly improving quality of life for chronic sufferers.

• Favorable Safety Profile for Most Patients: When used in patients with normal renal function and no contraindications, it is a well-tolerated and safe long-term option for prevention.

User-Centric and Practical Benefits

• Convenient Dosing Schedule: Twice-daily dosing for treatment is easy to adhere to.

• Cost-Effective Therapy: As a generic Nitrofurantoin, it is often a more affordable option compared to newer branded antibiotics.

• Minimal Disruption to Gut Microbiome: Its localized action means it is less likely to cause antibiotic-associated diarrhea or C. diff infection compared to broad-spectrum alternatives.

How Does Furolin Compare to Other UTI Antibiotics?

Furolin (Nitrofurantoin) vs. Common UTI Treatment Alternatives

Frequently Asked Questions (FAQs) About Furolin 100mg

Can I take Furolin for a kidney infection?
No, Furolin (Nitrofurantoin) is not recommended for the treatment of kidney infections (pyelonephritis) or any systemic infections. It does not achieve adequate tissue concentrations in the kidneys or bloodstream. Kidney infections require antibiotics that achieve high systemic levels.

How long does it take for Furolin to work for a UTI?
Most people start to experience relief from UTI symptoms like burning and urgency within 1 to 2 days of starting treatment. However, it is crucial to complete the entire prescribed course (usually 5-7 days) even if you feel better, to ensure the infection is fully eradicated and to prevent recurrence or resistance.

Can I drink alcohol while taking Nitrofurantoin tablets?
It is generally advised to avoid alcohol while taking any antibiotic, including Furolin. Alcohol can exacerbate some side effects like nausea, dizziness, or headache, and may place additional stress on the liver. It is best to abstain until you have finished the course.

Is Furolin safe for the elderly?
Furolin can be used in the elderly, but with extreme caution. Age-related decline in kidney function is common. Since Furolin is contraindicated in renal impairment, a doctor must assess kidney function via a blood test before prescribing. The risk of side effects like peripheral neuropathy and pulmonary reactions may also be higher.

What should I do if I miss a dose of my Furolin tablet?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this increases the risk of side effects.

Can Furolin be used for UTI prevention?
Yes, this is one of its key uses. For patients with recurrent UTIs (e.g., 2 or more in 6 months), a doctor may prescribe a long-term, low-dose prophylactic regimen, such as Furolin 50mg or 100mg once daily at bedtime, often for 6 months or longer. This is highly effective in reducing the frequency of infections.

Does Nitrofurantoin interact with birth control pills?
Unlike some antibiotics, Nitrofurantoin is not known to reduce the effectiveness of hormonal contraceptives (like birth control pills, patches, or rings). No interaction has been established. However, if you experience vomiting or severe diarrhea while taking Furolin, this could impair absorption of oral contraceptives, and a backup method should be used.