Description
Fercari IV Injection 500mg/10ml Price in Pakistan
Product Overview
Fercari IV Injection 500mg/10ml is a prescription intravenous iron replacement product containing the active ingredient Ferric Carboxymaltose. Manufactured by Hilton Pharma (Pvt) Ltd. in Pakistan, this advanced iron formulation is specifically designed to rapidly and effectively replenish iron stores in patients diagnosed with iron deficiency anemia (IDA) . It is primarily prescribed for adult patients who cannot tolerate oral iron supplements, those for whom oral iron therapy has failed, or individuals with non-dialysis-dependent chronic kidney disease. Fercari is administered as a slow intravenous push or infusion by a healthcare professional in a clinical setting, providing a convenient and efficient treatment option that can correct iron deficiency in just one or two sessions. Each pack contains 1 vial of 10ml solution.
This advanced intravenous iron therapy delivers rapid and effective correction of iron deficiency anemia:
Rapid Iron Replenishment: Quickly restores depleted iron stores to support hemoglobin formation and red blood cell production.
Effective for Multiple Conditions: Treats iron deficiency anemia in patients with chronic kidney disease, heart failure, and those unable to tolerate oral iron.
Convenient Dosing Schedule: Typically administered in two doses separated by at least 7 days, reducing the need for frequent hospital visits.
High Bioavailability: Ferric carboxymaltose is a colloidal iron (III) hydroxide complex that efficiently delivers iron to the body.
Minimal GI Side Effects: Bypasses the gastrointestinal tract, avoiding the common side effects associated with oral iron supplements.
Prescription Medication: Requires administration by a qualified healthcare professional in a medical setting.
What are the Primary Uses and Key Features of Fercari IV Injection?
Fercari IV Injection serves as a specialized therapeutic solution for managing iron deficiency anemia across various patient populations. It is designed to rapidly correct iron deficiency when oral supplements are not suitable or effective.
Core Uses of This Medication
Iron Deficiency Anemia: The primary indication is the treatment of iron deficiency anemia in adult patients. It rapidly replenishes iron stores to help form hemoglobin and improve red blood cell production.
Chronic Kidney Disease (CKD): Manages anemia in patients suffering from non-dialysis-dependent chronic kidney disease.
Heart Failure: Improves exercise capacity and reduces fatigue in certain adults with congestive heart failure caused by iron deficiency.
Heavy Menstrual Bleeding: Effective for patients with iron deficiency due to heavy menstrual bleeding.
Post-Surgical Blood Loss: Suitable for patients recovering from surgery who have experienced significant blood loss.
Oral Iron Intolerance: Specifically indicated for patients who cannot tolerate oral iron supplements or have had an unsatisfactory response to oral iron therapy.
Standout Product Features
| Feature | Description |
|---|---|
| Active Ingredient: Ferric Carboxymaltose | A colloidal iron (III) hydroxide complex that efficiently delivers iron to the body. |
| Strength: 500mg/10ml | Each vial contains 500mg of elemental iron in a 10ml solution. |
| Manufacturer: Hilton Pharma | Manufactured by a reputable Pakistani pharmaceutical company. |
| Intravenous Administration | Administered as a slow IV push or infusion by a healthcare professional. |
| Rapid Action | Quickly replenishes iron stores and reduces symptoms of anemia such as fatigue and weakness. |
| Convenient Dosing | Typically given in two doses separated by at least 7 days. |
| Prescription Required | Available only with a prescription from a qualified healthcare professional. |
| Single-Use Vial | Each pack contains 1 vial of 10ml solution. |
How Does Ferric Carboxymaltose Work?
Ferric Carboxymaltose is a colloidal iron (III) hydroxide in complex with carboxymaltose, a carbohydrate polymer that releases iron. When administered intravenously, the carboxymaltose complex dissociates, releasing ferric iron (Fe³⁺) that binds to transferrin, a protein responsible for transporting iron in the bloodstream. This iron is then utilized by the body for the production of hemoglobin in red blood cells.
Key Benefits
Rapidly replenishes iron stores in the body.
Reduces symptoms of iron deficiency anemia such as fatigue and weakness.
Convenient and easy-to-administer injection form.
Suitable for patients who cannot tolerate oral iron supplements.
How Should I Use Fercari IV Injection Correctly?
Fercari IV Injection must be administered by a healthcare professional. Do not self-administer this medication.
Dosage and Administration
For Patients Weighing 50kg (110lb) or More: Give Ferric Carboxymaltose in two doses separated by at least 7 days. Give each dose as 750mg for a total cumulative dose not to exceed 1500 mg of iron per course.
For Patients Weighing Less Than 50kg (110lb): Give Ferric Carboxymaltose in two doses separated by at least 7 days. Give each dose as 15mg/kg body weight for a total cumulative dose not to exceed 1500mg of iron per course.
Administration: Administer Ferric Carboxymaltose intravenously, either as an undiluted slow intravenous push or by infusion.
Oral Iron Therapy: The absorption of oral iron is reduced when administered concomitantly with parenteral iron preparations. Therefore, if required, oral iron therapy should not be started for at least 5 days after the last injection.
Important Considerations
Prescription Only: This medication is available only with a prescription from a qualified healthcare professional.
Healthcare Professional Administration: Must be administered by a healthcare professional through an intravenous infusion.
Follow Instructions: Follow the healthcare provider’s instructions carefully and do not self-administer the medication.
What Precautions Should I Be Aware of Before Taking This Medication?
While generally safe and well-tolerated, specific conditions and interactions require awareness and caution.
When Not to Use (Contraindications)
Known Hypersensitivity: Do not use if you have a known hypersensitivity to the active substance, any of its excipients, or serious hypersensitivity to other parenteral iron products.
Anemia Not Due to Iron Deficiency: Do not use if anemia is not attributed to iron deficiency, e.g., other microcytic anemia.
Iron Overload: Do not use if there is evidence of iron overload or disturbances in the utilisation of iron.
Precautions
Acute or Chronic Infection: Parenteral iron must be used with caution in case of acute or chronic infection.
Asthma, Eczema, or Atopic Allergies: Use with caution in patients with asthma, eczema, or atopic allergies.
Ongoing Bacteremia: It is recommended that treatment with Ferric Carboxymaltose is stopped in patients with ongoing bacteremia.
Paravenous Leakage: Caution should be exercised to avoid paravenous leakage when administering Ferric Carboxymaltose.
Drug Interactions
Oral Iron: The absorption of oral iron is reduced when administered concomitantly with parenteral iron preparations. Oral iron therapy should not be started for at least 5 days after the last injection.
Are There Any Potential Side Effects of Fercari IV Injection?
As with all medications, Fercari IV Injection may cause side effects, although not everyone experiences them.
Common Side Effects
| Side Effect | Description |
|---|---|
| Nausea | Mild to moderate nausea may occur. |
| Dizziness | Some individuals may experience dizziness or lightheadedness. |
| Gastrointestinal Disturbances | Mild stomach discomfort may occur. |
| Headache | Mild to moderate headaches may occur. |
| Injection Site Reactions | Pain, redness, or swelling at the injection site. |
| Rash | Mild skin rash may occur. |
| Hypophosphatemia | Low phosphate levels in the blood. |
| Hypertension | Mild increase in blood pressure. |
Uncommon Side Effects
Anaphylaxis, arthralgia, back pain, chest pain, fatigue, flushing, hypotension, malaise, tachycardia, myalgia, paraesthesia, dysgeusia, peripheral oedema, chills, pruritus, pyrexia, rigors, urticaria.
Rare Side Effects
Dyspnoea, loss of consciousness, anxiety, phlebitis, syncope, flatulence, pallor.
When to Seek Immediate Medical Attention
Severe Allergic Reaction: Difficulty breathing, swelling of the face/lips/tongue/throat, severe dizziness, or extensive rash.
Signs of Anaphylaxis: Sudden onset of symptoms such as rash, itching, swelling, or difficulty breathing.
Severe Injection Site Reactions: Persistent pain, swelling, or redness at the injection site.
How Should I Store This Medication?
Proper storage is essential for maintaining the stability, efficacy, and safety of Fercari IV Injection.
Optimal Storage Conditions
Temperature Control: Store at room temperature away from moisture and heat.
Keep Out of Reach: Keep the medication out of reach of children and pets.
Check Solution: Do not use the medication if the solution is discolored or contains particles.
Single-Use Only: Each vial is for single use only. Discard any unused portion.
Who Manufactures Fercari IV Injection?
Fercari IV Injection is manufactured by Hilton Pharma (Pvt) Ltd. , a reputable Pakistani pharmaceutical company. Hilton Pharma is known for producing high-quality medications for various medical conditions.
Commitment to Quality and Safety
DRAP Approval: Registered with the Drug Regulatory Authority of Pakistan (DRAP).
GMP Compliance: Manufactured in facilities that follow strict Good Manufacturing Practices.
Quality Assurance: Each batch undergoes rigorous quality testing to ensure purity, potency, and consistency.
Patient Safety: A commitment to providing safe, effective, and high-quality medications.
How Does Ferric Carboxymaltose Compare to Other Iron Therapies?
Understanding the distinct advantages of Ferric Carboxymaltose (Fercari) helps in making an informed treatment decision.
Ferric Carboxymaltose vs. Iron Sucrose
| Feature | Ferric Carboxymaltose (Fercari) | Iron Sucrose |
|---|---|---|
| Active Ingredient | Ferric Carboxymaltose | Iron Sucrose |
| Dosing | Typically 2 doses separated by 7 days | Multiple smaller doses over several weeks |
| Convenience | Fewer hospital visits required | More frequent visits needed |
| Iron Repletion Rate | Higher rate of iron repletion goal achievement | More modest improvement in hemoglobin |
| Maximum Single Dose | Up to 750mg per dose | Typically 200-300mg per dose |
| Best For | Patients requiring rapid correction with fewer visits | Patients who prefer fractionated dosing |
Frequently Asked Questions (FAQs)
1. What is Fercari IV Injection used for?
Fercari IV Injection is used for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron, have had unsatisfactory response to oral iron, or have non-dialysis-dependent chronic kidney disease.
2. How much does Fercari IV Injection cost in Pakistan?
The price of Fercari IV Injection 500mg/10ml in Pakistan ranges from Rs. 2,660 to Rs. 2,800 per vial. Prices may vary depending on the pharmacy and location.
3. How is Fercari IV Injection administered?
Fercari IV Injection is administered intravenously by a healthcare professional, either as an undiluted slow intravenous push or by infusion.
4. How many doses are required?
Ferric Carboxymaltose is typically given in two doses separated by at least 7 days.
5. Can I take oral iron supplements with Fercari?
No. Oral iron therapy should not be started for at least 5 days after the last injection, as it may reduce the absorption of oral iron.
6. What are the common side effects?
Common side effects include nausea, dizziness, gastrointestinal disturbances, headache, injection site reactions, rash, hypophosphatemia, and hypertension.
7. Is Fercari IV Injection safe during pregnancy?
Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Use only if clearly needed and prescribed by your doctor.
8. Do I need a prescription for Fercari IV Injection?
Yes. Fercari IV Injection is a prescription medication and is available only with a prescription from a qualified healthcare professional.
9. Who manufactures Fercari IV Injection?
Fercari IV Injection is manufactured by Hilton Pharma (Pvt) Ltd. in Pakistan.
10. How should I store Fercari IV Injection?
Store at room temperature away from moisture and heat. Keep out of reach of children. Do not use if the solution is discolored or contains particles.
