Cefspan Cap 400Mg – Pakistan’s Premier Online Pharmacy

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Cefspan Cap 400mg contains Cefixime for bacterial infections like UTI, bronchitis & tonsillitis. Prescription antibiotic. Know uses, dosage & side effects.

Description

Cefspan Cap 400Mg are a potent prescription antibiotic medication formulated with the active ingredient Cefixime. This advanced third-generation cephalosporin is designed to effectively combat a broad spectrum of bacterial infections by disrupting the growth and integrity of harmful bacteria. It is a cornerstone treatment prescribed by healthcare professionals for common to moderate bacterial diseases.

Before using this medication, a confirmed diagnosis from a qualified doctor is essential, as antibiotics like Cefspan are ineffective against viral illnesses such as influenza or the common cold. This overview highlights the core attributes of this reliable antibiotic therapy.

✔️ Contains 400mg of pure Cefixime, a potent third-generation cephalosporin antibiotic.
✔️ Prescribed for respiratory, urinary tract, ear, throat, and skin infections.
✔️ Offers convenient once-daily dosing for improved patient adherence.
✔️ Manufactured under strict GMP (Good Manufacturing Practice) standards for assured quality and potency.
✔️ Works by bactericidal action, killing susceptible bacteria to resolve infection.

What is Cefspan Cap 400Mg Used For? Understanding Its Therapeutic Applications

Cefspan Cap 400Mg with Cefixime as its core component, is prescribed for bacterial infections caused by susceptible organisms. Its broad-spectrum activity makes it a versatile tool in a physician’s arsenal. Understanding its primary uses helps in recognizing its therapeutic value.

What Specific Infections Does Cefspan Cap 400Mg Treat?

Healthcare providers prescribe Cefspan Capsules for a variety of bacterial infections. The key therapeutic indications include:

  • Urinary Tract Infections (UTIs): Effectively treats uncomplicated cystitis (bladder infection) and pyelonephritis (kidney infection) caused by susceptible bacteria like E. coli.

  • Respiratory Tract Infections: Used for acute bacterial bronchitis, exacerbations of chronic bronchitis, and community-acquired pneumonia.

  • Ear, Nose, and Throat (ENT) Infections: A common choice for acute otitis media (middle ear infection), pharyngitis, and tonsillitis, particularly when caused by Streptococcus pyogenes.

  • Sexually Transmitted Infections (STIs): Treatment of uncomplicated gonorrhea (cervical/urethral).

  • Skin and Soft Tissue Infections: Manages mild to moderate bacterial infections of the skin and underlying structures.

  • Typhoid Fever: Used in the management of enteric fever caused by Salmonella typhi.

Active Pharmaceutical Ingredient: The Science Behind Cefspan

The efficacy of Cefspan 400mg stems from its singular, powerful active ingredient. This section details the component responsible for its antibacterial action.

What is the Key Ingredient in Cefspan Capsules?

The sole active ingredient in each Cefspan 400mg capsule is Cefixime 400mg. Cefixime belongs to the third-generation class of cephalosporin antibiotics. It is a semi-synthetic, broad-spectrum antimicrobial agent known for its stability against certain bacterial enzymes (beta-lactamases) that can inactivate other antibiotics. This gives it a reliable profile against a wider range of Gram-positive and Gram-negative bacteria compared to earlier generations.

Benefits of Cefixime as the Core Ingredient:

  • Broad-Spectrum Activity: Targets a wide array of pathogenic bacteria.

  • Bactericidal Action: Kills bacteria outright rather than just inhibiting growth, leading to faster resolution.

  • High Oral Bioavailability: Effectively absorbed when taken orally, ensuring the drug reaches the site of infection.

  • Convenient Pharmacokinetics: Allows for once-daily dosing in many cases due to its prolonged half-life in the body.

The capsules also contain inactive ingredients (excipients) like diluents, disintegrants, and lubricants, which are pharmacologically inert and aid in the capsule’s formation, stability, and dissolution.

How Should I Take Cefspan 400mg? Directions for Correct Use

Adhering to proper administration guidelines is crucial for the drug’s effectiveness and your safety. Always follow your doctor’s specific instructions, which override general guidance.

What is the Proper Way to Administer This Antibiotic?

For optimal results and to minimize potential gastrointestinal side effects, follow these directions:

  1. Swallow Whole: Take the capsule whole with a full glass of water. Do not crush, chew, or break it open.

  2. Timing with Food: Cefspan can be taken with or without food. However, taking it with a meal may help reduce the chance of stomach upset.

  3. Consistency is Key: Try to take your dose at the same time each day to maintain a constant level of the antibiotic in your bloodstream.

  4. Complete the Full Course: It is imperative to finish the entire prescribed course of antibiotics, even if you start feeling better after a few days. Stopping early can lead to antibiotic resistance and recurrence of the infection.

  5. Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Dosage Information: What is the Recommended Dosage of Cefspan?

The dosage of Cefspan 400mg is not one-size-fits-all; it is meticulously determined by a qualified healthcare professional based on multiple factors.

How is the Dosage of Cefixime Determined for My Infection?

Your doctor will decide the appropriate dose and duration. The following table outlines typical dosage regimens for adults, but your prescription may differ.

Infection Type Standard Adult Dosage Frequency Typical Duration Notes
Uncomplicated UTIs, Bronchitis 400 mg Once daily 7-14 days Commonly prescribed for 7 days.
Sore Throat (Pharyngitis/Tonsillitis) 400 mg Once daily 10 days A full 10-day course is critical for strep throat.
Uncomplicated Gonorrhea 400 mg Single Dose One time Often given as a single oral dose.
Other Infections (e.g., Otitis Media) 400 mg Once daily OR 200 mg Every 12 hours 10-14 days. Doctor will specify the regimen.

Important Dosage Considerations:

  • Renal Impairment: Dosage adjustment is necessary for patients with significantly reduced kidney function. Your doctor will calculate a modified dose.

  • Elderly Patients: Dose may be adjusted based on renal function.

  • Pediatric Use: Cefspan 400mg capsules are typically for adults. Pediatric doses are based on body weight using other formulations like oral suspension.

What Precautions Should I Take Before Using Cefspan 400mg?

Prior to initiating therapy, certain precautions must be observed to ensure safe and effective treatment. This information must be thoroughly discussed with your prescribing physician.

What Are the Critical Warnings and Contraindications?

  • Allergy Alert: Do not use Cefspan if you have a known hypersensitivity to Cefixime, any other cephalosporin antibiotic (e.g., cephalexin, cefuroxime), or any component of the capsule. Cross-allergenicity with penicillins may occur in up to 10% of patients with penicillin allergy. Inform your doctor of any past allergic reactions to antibiotics.

  • Pseudomembranous Colitis: Antibiotic use can cause an overgrowth of Clostridium difficile, leading to severe, persistent diarrhea. Inform your doctor immediately if you experience watery or bloody stools during or after treatment.

  • Kidney Function: Patients with renal impairment require dose modification. Your doctor may order tests to assess your kidney function.

  • Liver Function: Use with caution in patients with liver disorders, as rare cases of hepatotoxicity have been reported.

  • Pregnancy and Lactation: Use during pregnancy only if clearly needed. Cefixime is excreted in human milk in small amounts; caution is advised while breastfeeding. Consult your doctor.

  • Drug Interactions: Inform your doctor about all medications you are taking, especially:

    • Carbamazepine: Cefixime may increase its blood levels.

    • Warfarin: May potentiate its anticoagulant effect.

    • Potent Diuretics: Like furosemide, may affect renal function.

What are the Possible Side Effects of Cefspan Capsules?

Like all medicines, Cefspan can cause side effects, although not everybody gets them. Being aware helps in early identification and management.

Common and Less Common Adverse Reactions

Common Side Effects (Generally Mild to Moderate):

  • Gastrointestinal disturbances: Diarrhea, loose stools, nausea, abdominal pain, dyspepsia, flatulence.

  • Central Nervous System: Headache, dizziness.

  • Others: Vaginal yeast infection (candidiasis) due to alteration of normal flora.

Less Common but Serious Side Effects (Require Immediate Medical Attention):

  • Severe Allergic Reactions: Symptoms include skin rash, itching, hives, swelling of the face/lips/tongue/throat (angioedema), difficulty breathing.

  • Severe Diarrhea/Pseudomembranous Colitis: Watery, severe diarrhea that may be bloody, accompanied by stomach cramps and fever.

  • Skin Reactions: Severe blistering skin rashes (e.g., Stevens-Johnson Syndrome).

  • Hepatobiliary Disorders: Symptoms of liver problems like jaundice (yellowing of skin/eyes), dark urine, severe nausea.

  • Blood Disorders: Unusual bleeding or bruising, signs of anemia (extreme tiredness).

  • Renal Dysfunction: Decreased urine output.

If you experience any severe or persistent side effects, discontinue use and contact your doctor promptly.

How Should I Store Cefspan 400mg Capsules?

Proper storage ensures the stability, potency, and safety of the medication throughout its shelf life.

What are the Ideal Storage Conditions for This Antibiotic?

  • Temperature: Store at room temperature, preferably between 20°C to 25°C (68°F to 77°F). Avoid freezing.

  • Environment: Keep the capsules in their original blister pack or container. Protect from excessive moisture and direct light.

  • Access: Store in a secure place out of the reach and sight of children and pets.

  • Disposal: Do not use after the expiration date printed on the pack. Dispose of unused medicine properly through a pharmacy take-back program; do not flush down the toilet or throw in household trash.

Who Manufactures Cefspan? Manufacturer Information

Cefspan is a well-established brand of Cefixime. It is originally researched and manufactured by Lupin Limited, a multinational pharmaceutical company headquartered in Mumbai, India. Lupin is recognized globally for its commitment to quality and is compliant with international Good Manufacturing Practice (GMP) standards set by regulatory bodies like the US FDA (Food and Drug Administration), MHRA (UK), and others.

The manufacturing processes adhere to stringent quality control protocols at every stage, from sourcing raw materials (Active Pharmaceutical Ingredient – API) to final packaging. This ensures that every Cefspan 400mg capsule delivers the specified dose of pure, effective Cefixime consistently.

What are the Key Benefits of Choosing Cefspan 400mg?

Opting for Cefspan 400mg as per your doctor’s prescription offers several distinct advantages in managing bacterial infections.

  • Targeted Bacterial Elimination: Its bactericidal mechanism ensures direct killing of a wide range of susceptible bacteria, leading to effective infection clearance.

  • Convenience of Dosing: The once-daily dosing regimen (for most infections) promotes better patient compliance compared to antibiotics requiring multiple daily doses.

  • Proven Clinical Efficacy: As a third-generation cephalosporin, Cefixime has a long history of clinical use and proven effectiveness in treating common community-acquired infections.

  • Quality Assurance: Manufactured under strict GMP conditions by a reputed pharmaceutical company, ensuring high standards of purity, safety, and consistent potency.

  • Oral Administration: Being an oral capsule, it allows for outpatient treatment, avoiding the need for hospital visits for injections in suitable cases.

How Does Cefspan Compare to Other Common Antibiotics?

Patients and healthcare providers often consider alternatives. This comparison highlights Cefspan’s position relative to other antibiotic classes.

Feature Cefspan (Cefixime) Amoxicillin Azithromycin Ciprofloxacin
Drug Class 3rd Gen Cephalosporin Penicillin Macrolide Fluoroquinolone
Spectrum Broad (Gram- & Gram+) Narrow to Broad Broad (Atypical coverage) Broad (Gram- focus)
Dosing Frequency Once or twice daily 2-3 times daily Once daily (short course) 1-2 times daily
Key Use Cases UTIs, Bronchitis, ENT Ear infections, Strep throat Pneumonia, STIs, COPD exacerbation Complicated UTIs, GI infections
Food Interaction Can take with/without food Without food preferred Variable Avoid dairy/antacids
Common Side Effects Diarrhea, GI upset Diarrhea, rash GI upset, nausea GI upset, tendon risk
Resistance Profile Stable to many beta-lactamases Susceptible to beta-lactamases Increasing resistance in some areas Black box warnings for serious ADRs

Conclusion: Cefspan offers a balance of broad-spectrum coverage, convenient dosing, and a generally well-tolerated profile, making it a preferred choice for specific infections where its spectrum aligns with the suspected bacteria. It is not a substitute for penicillin in all cases or for macrolides in atypical pneumonia.

Frequently Asked Questions (FAQs) About Cefspan 400mg

This section addresses common patient queries with semantically rich answers tailored for search engines and voice assistants.

Is Cefspan 400mg a strong antibiotic?

Yes, Cefspan 400mg containing Cefixime is considered a potent broad-spectrum antibiotic. Its “strength” lies in its effectiveness against a wide range of bacteria and its stability against certain resistance mechanisms. However, antibiotic selection should always be based on the specific bacteria causing the infection, not a general notion of strength.

Can I take Cefspan for a throat infection or tonsillitis?

Cefspan is prescribed for bacterial pharyngitis and tonsillitis, often caused by Streptococcus pyogenes. It is crucial to confirm a bacterial cause through a rapid strep test or culture, as most sore throats are viral. A typical course for strep throat is 10 days to prevent complications like rheumatic fever.

How quickly does Cefspan start working for a UTI?

Patients often start experiencing symptom relief, such as reduced burning sensation, within 24 to 48 hours of taking the first dose, as the drug concentration builds up in the urine. However, it is vital to complete the full 5-7 day course as prescribed to completely eradicate the bacteria and prevent recurrence.

What should I avoid while taking Cefixime capsules?

Avoid taking antacids containing aluminum or magnesium within 2 hours of your dose, as they can interfere with absorption. It is generally advised to limit or avoid alcohol during any antibiotic course, as it can increase the risk of side effects like dizziness and stomach upset. Do not take any other medicine, including herbal supplements, without consulting your doctor.

Can Cefspan capsules be used for tooth infection?

Dental infections (odontogenic infections) are sometimes treated with Cefixime if the bacteria are susceptible. However, first-line antibiotics for dental abscesses are often amoxicillin or metronidazole. A dentist or doctor must assess the infection to prescribe the most appropriate antibiotic, which may include Cefspan in certain scenarios.

Is it safe to take Cefspan during pregnancy?

Cefixime is classified as a Pregnancy Category B drug in some pharmacopeias, meaning animal studies have not shown risk, but adequate human studies are lacking. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. A prescribing doctor will make this decision after a thorough evaluation.

What is the price of Cefspan 400mg?

The price of Cefspan 400mg capsules can vary based on country, pharmacy, pack size (strip of 4, 6, or 10 capsules), and local pricing policies. It is a prescription medicine, so cost information is best obtained from licensed pharmacies upon presenting a valid prescription.

Additional information

Weight 20 g

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